iPTMnet Report for Q9HAV4 (XPO5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HAV4 / XPO5_HUMAN
Protein Name Exportin-5
Gene Name Name: XPO5
Synonyms:KIAA1291,RANBP21;
Organism Homo sapiens (Human)

PRO ID PR:Q9HAV4
DAG View
PRO Name exportin-5 (human)
Definition An exportin-5 that is encoded in the genome of human.
Short Label hXPO5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HAV4 (XPO5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22223895
T26 Phosphorylation PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
K41 Acetylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
T169 Phosphorylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
T345 Phosphorylation Signor 27846390
T345 Phosphorylation P27361 (MAPK3) Signor 27846390
T345 Phosphorylation P28482 (MAPK1) Signor 27846390
S369 Phosphorylation PhosphoSitePlus
T374 Phosphorylation PhosphoSitePlus
K396 Acetylation PhosphoSitePlus   UniProt 19608861
K396 Ubiquitination PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
T414 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus   Signor 27846390
S416 Phosphorylation P27361 (MAPK3) Signor 27846390
S416 Phosphorylation P28482 (MAPK1) Signor 27846390
C419 Methylation IEDB 31844290
C419 S-Nitrosylation dbSNO 26338901
S428 Phosphorylation PhosphoSitePlus
R448 Methylation PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus   Signor 27846390
S497 Phosphorylation P27361 (MAPK3) Signor 27846390
S497 Phosphorylation P28482 (MAPK1) Signor 27846390
K590 Ubiquitination PhosphoSitePlus
C605 Methylation IEDB 31844290
S606 Phosphorylation PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus
K610 Ubiquitination PhosphoSitePlus
Y662 Phosphorylation PhosphoSitePlus
C706 S-Nitrosylation dbSNO 26338901
C714 S-Nitrosylation dbSNO 26338901
S722 Phosphorylation HPRD 20068231
Y753 Phosphorylation PhosphoSitePlus
S755 Phosphorylation PhosphoSitePlus
S756 Phosphorylation PhosphoSitePlus
T782 Phosphorylation PhosphoSitePlus
T785 Phosphorylation PhosphoSitePlus
Y787 Phosphorylation PhosphoSitePlus
T800 Phosphorylation PhosphoSitePlus
K801 Ubiquitination PhosphoSitePlus
K810 Acetylation PhosphoSitePlus
K810 Ubiquitination PhosphoSitePlus
S826 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 20068231
C847 Methylation IEDB 31844290
Y922 Phosphorylation PhosphoSitePlus
K930 Ubiquitination PhosphoSitePlus
K1132 Ubiquitination PhosphoSitePlus
S1137 Phosphorylation HPRD   PhosphoSitePlus 20068231
K1140 Ubiquitination PhosphoSitePlus
K1160 Ubiquitination PhosphoSitePlus
K1173 Ubiquitination PhosphoSitePlus
S1177 Phosphorylation PhosphoSitePlus
K1180 Ubiquitination PhosphoSitePlus
T1182 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S369 Y369 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S416 N416 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S497 * Biomuta DOID:363 / uterine cancer [ cosmic ]
K610 N610 Biomuta DOID:363 / uterine cancer [ icgc ]
S722 T722 Biomuta DOID:10534 / stomach cancer [ icgc ]
Y753 F753 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S756 T756 Biomuta DOID:1612 / breast cancer [ cosmic ]
K810 T810 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S826 C826 Biomuta [ cosmic ] DOID:1612 / breast cancer [ icgc ]
K1140 I1140 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1173 T1173 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]