iPTMnet Report for Q9HAT8 (PELI2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HAT8 / PELI2_HUMAN
Protein Name E3 ubiquitin-protein ligase pellino homolog 2
Gene Name Name: PELI2
Organism Homo sapiens (Human)

PRO ID PR:Q9HAT8
DAG View
PRO Name E3 ubiquitin-protein ligase pellino homolog 2 (human)
Definition An E3 ubiquitin-protein ligase pellino homolog 2 that is encoded in the genome of human.
Short Label hPELI2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HAT8 (PELI2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
S3 Phosphorylation PhosphoSitePlus
R36 Methylation PhosphoSitePlus
R38 Methylation PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
K50 Acetylation PhosphoSitePlus
K55 Acetylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
T64 Phosphorylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
Y81 Phosphorylation PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
Y151 Phosphorylation PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K176 Acetylation PhosphoSitePlus
T252 Phosphorylation PhosphoSitePlus
T264 Phosphorylation PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
T290 Phosphorylation P51617 (IRAK1) PRO   PhosphoSitePlus 19264966
S295 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000027058 (hPELI2/Phos:1) pT290 PRO 19264966
PR:000048741 (hPELI2/PhosRes+) p PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R36 I36 Biomuta DOID:363 / uterine cancer [ icgc ]
R38 L38 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
R38 Q38 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1612 / breast cancer [ cosmic ]
R38 W38 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T64 M64 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S80 F80 Biomuta DOID:4159 / skin cancer [ cosmic ]
K176 E176 Biomuta DOID:1324 / lung cancer [ cosmic ]
T290 I290 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]