iPTMnet Report for Q9HAP2 (MLXIP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HAP2 / MLXIP_HUMAN
Protein Name MLX-interacting protein
Gene Name Name: MLXIP
Synonyms:BHLHE36,KIAA0867,MIR;
Organism Homo sapiens (Human)

PRO ID PR:Q9HAP2
DAG View
PRO Name MLX-interacting protein (human)
Definition An MLX-interacting protein that is encoded in the genome of human.
Short Label hMLXIP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HAP2 (MLXIP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
S9 Phosphorylation PhosphoSitePlus   UniProt 23186163
S27 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S33 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S39 Phosphorylation PhosphoSitePlus
K140 Methylation PhosphoSitePlus
S143 Phosphorylation RLIMS-P 22506051
T187 Phosphorylation RLIMS-P 22506051
K209 Ubiquitination PhosphoSitePlus
Y222 Phosphorylation PhosphoSitePlus   RLIMS-P 36398713
Y252 Phosphorylation PhosphoSitePlus
S482 O-Glycosylation GlyGen 33214551, 26315267, 30379171, ...28411811, 29351928, 34019948, 30620550, 35138101, 35289036, 35132862, 29237092, 30059200
T485 O-Glycosylation GlyGen 33214551, 26315267, 30379171, ...28411811, 29351928, 34019948, 30620550, 35138101, 35289036, 35132862, 29237092, 30059200
T487 O-Glycosylation GlyGen 33214551, 26315267, 30379171, ...28411811, 29351928, 34019948, 30620550, 35138101, 35289036, 35132862, 29237092, 30059200
S489 O-Glycosylation GlyGen 33214551, 26315267, 30379171, ...28411811, 29351928, 34019948, 30620550, 35138101, 35289036, 35132862, 29237092, 30059200
K595 Sumoylation PhosphoSitePlus
S602 O-Glycosylation GlyGen 33214551, 26315267, 30379171, ...28411811, 29351928, 34019948, 30620550, 35138101, 35289036, 35132862, 29237092, 30059200
T603 O-Glycosylation GlyGen 33214551, 26315267, 30379171, ...32938750, 28411811, 30059200, 34019948, 35132862, 30620550, 35138101, 35289036, 29351928, 29237092
S605 O-Glycosylation GlyGen 33214551, 26315267, 30379171, ...32938750, 28411811, 30059200, 34019948, 35132862, 30620550, 35138101, 35289036, 29351928, 29237092
S607 O-Glycosylation GlyGen 33214551, 26315267, 30379171, ...28411811, 29351928, 34019948, 30620550, 35138101, 35289036, 35132862, 29237092, 30059200
S640 Phosphorylation PhosphoSitePlus
S669 Phosphorylation PhosphoSitePlus   UniProt 23186163
T673 O-Glycosylation GlyGen 32938750
T675 O-Glycosylation GlyGen 33214551, 26315267, 30379171, ...32938750, 28411811, 30059200, 34019948, 35132862, 30620550, 35138101, 35289036, 29351928, 29237092
S700 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S27 Phosphorylation HPRD 18669648
S33 Phosphorylation HPRD 18669648
S700 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T487 M487 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S489 C489 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S602 A602 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S602 F602 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S602 P602 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]