Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9HAN9 / NMNA1_HUMAN
Protein Name Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
Gene Name Name: NMNAT1
Organism Homo sapiens (Human)

DAG View
PRO Name nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 (human)
Definition A nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 that is encoded in the genome of human.
Short Label hNMNAT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9HAN9 (NMNAT1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
T7 Phosphorylation PhosphoSitePlus
Y41 Phosphorylation PhosphoSitePlus
Y55 Phosphorylation PhosphoSitePlus
Y64 Phosphorylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
S117 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 18220336, ...24275569, 20166139
T119 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 20068231, 17081983, 24275569, ...18220336
K128 Ubiquitination PhosphoSitePlus
S136 Phosphorylation P17252 (PRKCA) PhosphoSitePlus 17360427
S208 Phosphorylation HPRD 17322306
K250 Ubiquitination PhosphoSitePlus
R261 Methylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T7 N7 Biomuta DOID:0070003 / blastoma [ cosmic ]
K250 N250 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:1612 / breast cancer [ cosmic, icgc, tcga ]