iPTMnet Report for Q9HAN9 (NMNAT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HAN9 / NMNA1_HUMAN
Protein Name Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
Gene Name Name: NMNAT1
Synonyms:NMNAT;
Organism Homo sapiens (Human)

PRO ID PR:Q9HAN9
DAG View
PRO Name nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 (human)
Definition A nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 that is encoded in the genome of human.
Short Label hNMNAT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HAN9 (NMNAT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T7 Phosphorylation PhosphoSitePlus
Y41 Phosphorylation PhosphoSitePlus
Y55 Phosphorylation PhosphoSitePlus
Y64 Phosphorylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
S117 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 18220336, ...24275569, 20166139
T119 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 24275569, 17081983, 20068231, ...18220336
K128 Ubiquitination PhosphoSitePlus
S136 Phosphorylation P17252 (PRKCA) PhosphoSitePlus 17360427
S208 Phosphorylation HPRD 17322306
K250 Ubiquitination PhosphoSitePlus
R261 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T7 N7 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S109 T109 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K250 N250 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]