iPTMnet Report for Q9HAF1 (MEAF6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HAF1 / EAF6_HUMAN
Protein Name Chromatin modification-related protein MEAF6
Gene Name Name: MEAF6
Synonyms:C1orf149,CENP-28,EAF6;
Organism Homo sapiens (Human)

PRO ID PR:Q9HAF1
DAG View
PRO Name chromatin modification-related protein MEAF6 (human)
Definition A chromatin modification-related protein MEAF6 that is encoded in the genome of human.
Short Label hMEAF6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HAF1 (MEAF6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Ubiquitination PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
K69 Acetylation PhosphoSitePlus   UniProt 19608861
K74 Acetylation PhosphoSitePlus   UniProt 19608861
K91 Acetylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
K113 Sumoylation PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
S118 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T120 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S122 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T124 Phosphorylation PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
K169 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S71 Phosphorylation HPRD 20068231
S118 Phosphorylation HPRD 18669648, 20068231
T120 Phosphorylation HPRD 18669648, 20068231
S122 Phosphorylation HPRD 18669648, 20068231
T124 Phosphorylation HPRD 20068231
S125 Phosphorylation HPRD 20068231
S136 Phosphorylation HPRD 17525332
S146 Phosphorylation HPRD 19007248


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K91 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ]
S125 Y125 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S136 I136 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S160 F160 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]