iPTMnet Report for Q9HA47 (UCK1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HA47 / UCK1_HUMAN
Protein Name Uridine-cytidine kinase 1
Gene Name Name: UCK1
Synonyms:URK1;
Organism Homo sapiens (Human)

PRO ID PR:Q9HA47
DAG View
PRO Name uridine-cytidine kinase 1 (human)
Definition A uridine-cytidine kinase 1 that is encoded in the genome of human.
Short Label hUCK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HA47 (UCK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
R66 Methylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
Y84 Phosphorylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
S145 Phosphorylation RLIMS-P 31938050
R165 Methylation PhosphoSitePlus
T202 Phosphorylation PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
C236 Methylation IEDB 31844290
S243 Phosphorylation PhosphoSitePlus
T251 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S253 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569
T263 Phosphorylation PhosphoSitePlus
K266 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation HPRD 19413330
S11 Phosphorylation HPRD 19413330
S29 Phosphorylation HPRD 19413330
T251 Phosphorylation HPRD 18669648
S253 Phosphorylation HPRD 18669648


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9HA47 (UCK1) S145 O95198 (KLHL2) unknown eFIP 31938050


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 L3 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
K76 T76 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S145 N145 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K203 R203 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S243 F243 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]