iPTMnet Report for Q9H9S3 (SEC61A2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H9S3 / S61A2_HUMAN
Protein Name Protein transport protein Sec61 subunit alpha isoform 2
Gene Name Name: SEC61A2
Organism Homo sapiens (Human)

PRO ID PR:Q9H9S3
DAG View
PRO Name protein transport protein Sec61 subunit alpha isoform 2 (human)
Definition A protein transport protein Sec61 subunit alpha isoform 2 that is encoded in the genome of human.
Short Label hSEC61A2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H9S3 (SEC61A2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K4 Ubiquitination PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
T75 Phosphorylation PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
T86 Phosphorylation PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
T105 Phosphorylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
R405 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S33 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T105 S105 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K388 R388 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K392 E392 Biomuta DOID:184 / bone cancer [ cosmic ]
K395 T395 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]