iPTMnet Report for Q9H9Q2 (COPS7B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H9Q2 / CSN7B_HUMAN
Protein Name COP9 signalosome complex subunit 7b
Gene Name Name: COPS7B
Synonyms:CSN7B;
Organism Homo sapiens (Human)

PRO ID PR:Q9H9Q2
DAG View
PRO Name COP9 signalosome complex subunit 7b (human)
Definition A COP9 signalosome complex subunit 7b that is encoded in the genome of human.
Short Label hCOPS7B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H9Q2 (COPS7B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 18850735
K95 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
C110 S-Nitrosylation dbSNO 19483679
K118 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
C240 S-Nitrosylation dbSNO 19483679
S254 Phosphorylation PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
S261 Phosphorylation UniProt 19690332
R263 Phosphorylation UniProt 19690332
Site PTM Type PTM Enzyme Score Source PMID
T219 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T261 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K95 E95 Biomuta DOID:4159 / skin cancer [ cosmic ]
S225 F225 Biomuta DOID:4159 / skin cancer [ cosmic ]
C240 Y240 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S261 A261 Biomuta DOID:4159 / skin cancer [ cosmic ]
T261 M261 Biomuta DOID:1319 / brain cancer [ cosmic ]
R263 C263 Biomuta DOID:2531 / hematologic cancer [ cosmic ]