iPTMnet Report for Q9H9J4 (USP42)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H9J4 / UBP42_HUMAN
Protein Name Ubiquitin carboxyl-terminal hydrolase 42
Gene Name Name: USP42
Organism Homo sapiens (Human)

PRO ID PR:Q9H9J4
DAG View
PRO Name ubiquitin carboxyl-terminal hydrolase 42 (human)
Definition A ubiquitin carboxyl-terminal hydrolase 42 that is encoded in the genome of human.
Short Label hUSP42
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H9J4 (USP42) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y63 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus   UniProt 23186163
K91 Ubiquitination PhosphoSitePlus
Y237 Phosphorylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
Y289 Phosphorylation PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
T422 Phosphorylation PhosphoSitePlus
T425 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
S431 Phosphorylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
S438 Phosphorylation PhosphoSitePlus
S479 Phosphorylation PhosphoSitePlus
S483 Phosphorylation PhosphoSitePlus   UniProt 23186163
S494 Phosphorylation PhosphoSitePlus
Y607 Phosphorylation PhosphoSitePlus
S611 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S612 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S615 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S619 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S754 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 23186163
S759 Phosphorylation PhosphoSitePlus
T783 Phosphorylation PhosphoSitePlus
S829 Phosphorylation PhosphoSitePlus
S832 Phosphorylation PhosphoSitePlus
S856 O-Glycosylation GlyGen 36240223
S856 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...15302935, 18669648, 24275569, 19690332, 20068231
S919 Phosphorylation PhosphoSitePlus
S936 Phosphorylation PhosphoSitePlus
Y953 Phosphorylation PhosphoSitePlus
S1007 Phosphorylation PhosphoSitePlus
S1026 Phosphorylation PhosphoSitePlus
Y1066 Phosphorylation PhosphoSitePlus
Y1069 Phosphorylation PhosphoSitePlus
S1115 Phosphorylation PhosphoSitePlus
S1116 Phosphorylation PhosphoSitePlus
S1133 Phosphorylation PhosphoSitePlus
S1148 Phosphorylation PhosphoSitePlus
S1166 Phosphorylation PhosphoSitePlus
S1170 Phosphorylation PhosphoSitePlus
S1181 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1184 Acetylation PhosphoSitePlus
K1191 Acetylation PhosphoSitePlus
K1191 Ubiquitination PhosphoSitePlus
K1193 Ubiquitination PhosphoSitePlus
K1194 Ubiquitination PhosphoSitePlus
S1213 Phosphorylation PhosphoSitePlus
S1219 Phosphorylation PhosphoSitePlus
S1222 Phosphorylation PhosphoSitePlus
S1226 Phosphorylation PhosphoSitePlus   UniProt 17081983
S1247 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1263 Phosphorylation PhosphoSitePlus
S1280 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S483 Phosphorylation HPRD 18452278
S611 Phosphorylation HPRD 18669648, 20068231
S612 Phosphorylation HPRD 18669648, 20068231
S615 Phosphorylation HPRD 19651622, 18669648, 20068231
S619 Phosphorylation HPRD 18669648
S754 Phosphorylation HPRD 19664995, 20068231, 18452278
S759 Phosphorylation HPRD 20068231
T772 Phosphorylation HPRD 20068231
S829 Phosphorylation HPRD 20068231
S832 Phosphorylation HPRD 20068231
S856 Phosphorylation HPRD 19413330, 17081983, 19664995, ...18452278, 19651622, 18669648, 19415658, 20068231
S919 Phosphorylation HPRD 18452278
S936 Phosphorylation HPRD 19651622
Y953 Phosphorylation HPRD 18691976
S1219 Phosphorylation HPRD 18669648, 20068231
S1222 Phosphorylation HPRD 18669648, 20068231
S1226 Phosphorylation HPRD 18669648, 17081983, 20068231
S1247 Phosphorylation HPRD 18452278
S1280 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S483 N483 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S754 T754 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S832 C832 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S856 G856 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S856 N856 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1222 L1222 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1226 C1226 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1247 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ]