iPTMnet Report for Q9H9B4 (SFXN1)
Protein Information
UniProt AC / UniProt ID | Q9H9B4 / SFXN1_HUMAN |
Protein Name | Sideroflexin-1 |
Gene Name | Name: SFXN1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H9B4 |
PRO Name | sideroflexin-1 (human) |
Definition | A sideroflexin-1 that is encoded in the genome of human. |
Short Label | hSFXN1 |
Category | organism-gene |
Q9H9B4 (SFXN1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 19413330, 22814378 | ||
S19 | Phosphorylation | score1 | PhosphoSitePlus | |||
T20 | Phosphorylation | score1 | PhosphoSitePlus | |||
S46 | O-Glycosylation | score1 | GlyGen | 36240223, 34725712, 35083852, ... | ||
K49 | Ubiquitination | score1 | PhosphoSitePlus | |||
K72 | Acetylation | score1 | PhosphoSitePlus | |||
K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y75 | Phosphorylation | score1 | PhosphoSitePlus | |||
K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
S173 | Phosphorylation | score1 | PhosphoSitePlus | |||
K202 | Ubiquitination | score1 | PhosphoSitePlus | |||
K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
T227 | Phosphorylation | score1 | PhosphoSitePlus | |||
S232 | O-Glycosylation | score1 | GlyGen | 36240223, 34725712, 35083852, ... | ||
S232 | Phosphorylation | score1 | PhosphoSitePlus | |||
K305 | Ubiquitination | score1 | PhosphoSitePlus | |||
R314 | Methylation | score1 | PhosphoSitePlus | |||
Y317 | Phosphorylation | score1 | PhosphoSitePlus | |||
K320 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S19 | R19 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S19 | N19 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
Y75 | C75 | Biomuta | DOID:1785 / pituitary cancer [ cosmic ] | |
T227 | M227 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ] | |
S232 | F232 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] | |
R314 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] |