iPTMnet Report for Q9H9B4 (SFXN1)
Protein Information
| UniProt AC / UniProt ID | Q9H9B4 / SFXN1_HUMAN |
| Protein Name | Sideroflexin-1 |
| Gene Name | Name: SFXN1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H9B4 |
| PRO Name | sideroflexin-1 (human) |
| Definition | A sideroflexin-1 that is encoded in the genome of human. |
| Short Label | hSFXN1 |
| Category | organism-gene |
Q9H9B4 (SFXN1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S2 | Acetylation | score1 | UniProt | 19413330, 22814378 | ||
| S19 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T20 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S46 | O-Glycosylation | score1 | GlyGen | 36240223, 34725712, 35083852, ... | ||
| K49 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K72 | Acetylation | score1 | PhosphoSitePlus | |||
| K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y75 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S173 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K202 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T227 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S232 | O-Glycosylation | score1 | GlyGen | 36240223, 34725712, 35083852, ... | ||
| S232 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K305 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R314 | Methylation | score1 | PhosphoSitePlus | |||
| Y317 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K320 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S19 | R19 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S19 | N19 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
| Y75 | C75 | Biomuta | DOID:1785 / pituitary cancer [ cosmic ] | |
| T227 | M227 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ] | |
| S232 | F232 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] | |
| R314 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] |
DAG View