Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9H9B4 / SFXN1_HUMAN
Protein Name Sideroflexin-1
Gene Name Name: SFXN1
Organism Homo sapiens (Human)

DAG View
PRO Name sideroflexin-1 (human)
Definition A sideroflexin-1 that is encoded in the genome of human.
Short Label hSFXN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9H9B4 (SFXN1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 22814378
S19 Phosphorylation PhosphoSitePlus
T20 Phosphorylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
K72 Acetylation PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
Y75 Phosphorylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
T227 Phosphorylation PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
R314 Methylation PhosphoSitePlus
Y317 Phosphorylation PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S19 R19 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
T227 M227 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:263 / kidney cancer [ cosmic ]
S232 F232 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
R314 * Biomuta DOID:363 / uterine cancer [ tcga ] DOID:1319 / brain cancer [ icgc ] DOID:1909 / melanoma [ cosmic ] DOID:3070 / malignant glioma [ tcga ]