iPTMnet Report for Q9H9A6 (LRRC40)
Protein Information
| UniProt AC / UniProt ID | Q9H9A6 / LRC40_HUMAN |
| Protein Name | Leucine-rich repeat-containing protein 40 |
| Gene Name | Name: LRRC40 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H9A6 |
| PRO Name | leucine-rich repeat-containing protein 40 (human) |
| Definition | A leucine-rich repeat-containing protein 40 that is encoded in the genome of human. |
| Short Label | hLRRC40 |
| Category | organism-gene |
Q9H9A6 (LRRC40) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| R6 | Methylation | score1 | PhosphoSitePlus | |||
| R13 | Methylation | score1 | PhosphoSitePlus | |||
| K17 | Methylation | score1 | PhosphoSitePlus | |||
| T25 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S26 | Phosphorylation | score0 | HPRD | 20068231 | ||
| K37 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S38 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| S44 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| S71 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648, 20068231 | ||
| K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K93 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T98 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K132 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K141 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K210 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K220 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C264 | Methylation | score1 | IEDB | 31844290 | ||
| C264 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
| K302 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S303 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T348 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K356 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K363 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K370 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S377 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S379 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T381 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T383 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S389 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K409 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K434 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K442 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S452 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S457 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T475 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T569 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R13 | H13 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S26 | * | Biomuta | DOID:1540 / parathyroid carcinoma [ cosmic ] | |
| S26 | L26 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| K37 | N37 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S71 | L71 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
| K132 | T132 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S303 | F303 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T381 | A381 | Biomuta | DOID:4362 / cervical cancer [ icgc ] | |
| T383 | I383 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
| K434 | N434 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K434 | M434 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] |
DAG View