iPTMnet Report for Q9H9A5 (CNOT10)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H9A5 / CNO10_HUMAN
Protein Name CCR4-NOT transcription complex subunit 10
Gene Name Name: CNOT10
Organism Homo sapiens (Human)

PRO ID PR:Q9H9A5
DAG View
PRO Name CCR4-NOT transcription complex subunit 10 (human)
Definition A CCR4-NOT transcription complex subunit 10 that is encoded in the genome of human.
Short Label hCNOT10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H9A5 (CNOT10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
K28 Ubiquitination PhosphoSitePlus
C46 Methylation IEDB 31844290
K58 Ubiquitination PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
T162 Phosphorylation PhosphoSitePlus
K177 Acetylation PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
T245 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
K256 Acetylation PhosphoSitePlus
K256 Methylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
R263 Methylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
C377 Methylation IEDB 31844290
K404 Ubiquitination PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
C504 S-Nitrosylation dbSNO 26338901
K513 Ubiquitination PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
K525 Ubiquitination PhosphoSitePlus
K564 Ubiquitination PhosphoSitePlus
C633 S-Nitrosylation dbSNO 26338901
K664 Ubiquitination PhosphoSitePlus
K713 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S241 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S249 F249 Biomuta DOID:4159 / skin cancer [ cosmic ]
R263 G263 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K286 N286 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K412 E412 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]