iPTMnet Report for Q9H992 (MARCHF7)
Protein Information
UniProt AC / UniProt ID | Q9H992 / MARH7_HUMAN |
Protein Name | E3 ubiquitin-protein ligase MARCHF7 |
Gene Name | Name: MARCHF7 Synonyms:AXOT,MARCH7,RNF177; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H992 |
PRO Name | E3 ubiquitin-protein ligase MARCHF7 (human) |
Definition | An E3 ubiquitin-protein ligase MARCHF7 that is encoded in the genome of human. |
Short Label | hMARCHF7 |
Category | organism-gene |
Q9H992 (MARCHF7) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22814378 | ||
K4 | Ubiquitination | score1 | PhosphoSitePlus | |||
S13 | Phosphorylation | score1 | PhosphoSitePlus | |||
S26 | Phosphorylation | score1 | PhosphoSitePlus | |||
S28 | Phosphorylation | score1 | PhosphoSitePlus | |||
R29 | Methylation | score1 | PhosphoSitePlus | |||
S31 | Phosphorylation | score1 | PhosphoSitePlus | |||
T36 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y37 | Phosphorylation | score1 | PhosphoSitePlus | |||
K93 | Ubiquitination | score1 | PhosphoSitePlus | |||
S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
S127 | Phosphorylation | score1 | PhosphoSitePlus | |||
S129 | Phosphorylation | score1 | PhosphoSitePlus | |||
S179 | Phosphorylation | score1 | PhosphoSitePlus | |||
S218 | Phosphorylation | score1 | PhosphoSitePlus | |||
S221 | Phosphorylation | score1 | PhosphoSitePlus | |||
S224 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
T238 | Phosphorylation | score1 | PhosphoSitePlus | |||
S243 | Phosphorylation | score1 | PhosphoSitePlus | |||
S245 | Phosphorylation | score1 | PhosphoSitePlus | |||
S271 | Phosphorylation | score1 | PhosphoSitePlus | |||
S284 | Phosphorylation | score1 | PhosphoSitePlus | |||
S288 | Phosphorylation | score1 | PhosphoSitePlus | |||
S300 | Phosphorylation | score1 | PhosphoSitePlus | |||
S314 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y315 | Phosphorylation | score1 | PhosphoSitePlus | |||
S317 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S324 | Phosphorylation | score1 | PhosphoSitePlus | |||
S359 | Phosphorylation | score1 | PhosphoSitePlus | |||
S368 | Phosphorylation | score1 | PhosphoSitePlus | |||
S389 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T395 | Phosphorylation | score1 | PhosphoSitePlus | |||
R406 | Methylation | score1 | PhosphoSitePlus | |||
S428 | Phosphorylation | score1 | PhosphoSitePlus | |||
K522 | Ubiquitination | score1 | PhosphoSitePlus | |||
K536 | Ubiquitination | score1 | PhosphoSitePlus | |||
S544 | Phosphorylation | score1 | PhosphoSitePlus | |||
K585 | Ubiquitination | score1 | PhosphoSitePlus | |||
K586 | Ubiquitination | score1 | PhosphoSitePlus | |||
K591 | Ubiquitination | score1 | PhosphoSitePlus | |||
S597 | Phosphorylation | score1 | PhosphoSitePlus | |||
K608 | Ubiquitination | score1 | PhosphoSitePlus | |||
K610 | Ubiquitination | score1 | PhosphoSitePlus | |||
T686 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
S687 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
S691 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T238 | Phosphorylation | score0 | HPRD | 18077418 | ||
S243 | Phosphorylation | score0 | HPRD | 18077418 | ||
S245 | Phosphorylation | score0 | HPRD | 18077418 | ||
S544 | Phosphorylation | score0 | HPRD | 19664994 | ||
T686 | Phosphorylation | score0 | HPRD | 18669648 | ||
S687 | Phosphorylation | score0 | HPRD | 18669648 | ||
S691 | Phosphorylation | score0 | HPRD | 18669648 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S13 | Y13 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
R29 | K29 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
T36 | A36 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K93 | E93 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S179 | L179 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S221 | Y221 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T238 | M238 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S245 | C245 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y315 | F315 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S317 | F317 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
R406 | T406 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
K522 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] |