iPTMnet Report for Q9H900 (ZWILCH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H900 / ZWILC_HUMAN
Protein Name Protein zwilch homolog
Gene Name Name: ZWILCH
Organism Homo sapiens (Human)

PRO ID PR:Q9H900
DAG View
PRO Name protein zwilch homolog (human)
Definition A protein zwilch that is encoded in the genome of human.
Short Label hZWILCH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H900 (ZWILCH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T74 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
T85 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus   UniProt 18691976
S91 Phosphorylation PhosphoSitePlus
T92 Phosphorylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
T316 Phosphorylation PhosphoSitePlus
T320 Phosphorylation PhosphoSitePlus
T324 Phosphorylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
C369 Methylation IEDB 31844290
K527 Ubiquitination PhosphoSitePlus
S565 Phosphorylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S82 Phosphorylation HPRD 18669648
T85 Phosphorylation HPRD 18691976
S88 Phosphorylation HPRD 18691976, 18669648, 20068231
S91 Phosphorylation HPRD 18691976, 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T74 A74 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S82 C82 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S91 Y91 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, icgc ] DOID:1781 / thyroid cancer [ icgc ]
T324 A324 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S344 G344 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S565 L565 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]