iPTMnet Report for Q9H8Y8 (GORASP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H8Y8 / GORS2_HUMAN
Protein Name Golgi reassembly-stacking protein 2
Gene Name Name: GORASP2
Synonyms:GOLPH6;
Organism Homo sapiens (Human)

PRO ID PR:Q9H8Y8
DAG View
PRO Name Golgi reassembly-stacking protein 2 (human)
Definition A Golgi reassembly-stacking protein 2 that is encoded in the genome of human.
Short Label hGORASP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H8Y8 (GORASP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 27062250, 11101516, 25255805, ...25807930
S4 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
K50 Acetylation PhosphoSitePlus
T54 Phosphorylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
Y72 Phosphorylation PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
T204 Phosphorylation PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
S214 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17287340, 20068231, 24275569
T222 Phosphorylation P28482 (MAPK1) , P27361 (MAPK3) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   UniProt 17287340, 17081983, 11408587, ...24275569, 23186163, 20068231
T225 Phosphorylation P27361 (MAPK3) , P24941 (CDK2) , P28482 (MAPK1) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   Signor   UniProt 23186163, 17081983, 18847512, ...11408587, 24275569, 17287340, 20068231
S245 Phosphorylation PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
S260 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...32574038, 34725712, 30620550, 34019948, 35138101, 32119511, 29689198, 29351928, 28657654
S262 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...32574038, 34725712, 30620550, 34019948, 35138101, 32119511, 29689198, 29351928, 28657654
S263 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...32574038, 34725712, 30620550, 34019948, 35138101, 32119511, 29689198, 29351928, 28657654
S269 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...32574038, 34725712, 30620550, 34019948, 35138101, 32119511, 29689198, 29351928, 28657654
T274 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...32574038, 34725712, 30620550, 34019948, 35138101, 32119511, 29689198, 29351928, 28657654
T301 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...32574038, 34725712, 30620550, 34019948, 35138101, 32119511, 29689198, 29351928, 28657654
S386 Phosphorylation PhosphoSitePlus
S391 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...32574038, 34725712, 30620550, 34019948, 35138101, 32119511, 29689198, 29351928, 28657654
S408 Phosphorylation PhosphoSitePlus
S409 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...32574038, 34725712, 30620550, 34019948, 35138101, 32119511, 29689198, 29351928, 28657654
S409 Phosphorylation PhosphoSitePlus
T411 Phosphorylation PhosphoSitePlus
T415 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16964243, 20068231, ...17081983
T418 Phosphorylation PhosphoSitePlus
T423 O-Glycosylation GlyGen 32574038
T423 Phosphorylation PhosphoSitePlus
T424 O-Glycosylation GlyGen 32574038, 30620550
R428 Methylation PhosphoSitePlus
S432 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T433 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S436 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S441 Phosphorylation PhosphoSitePlus   UniProt 27062250, 21884936
S449 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 27062250, 18669648
S451 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 27062250, ...18669648, 19690332
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 18452278
S214 Phosphorylation HPRD 19651622, 20068231
T222 Phosphorylation HPRD 19413330, 17287340, 17081983, ...19664995, 19651622, 20068231
T225 Phosphorylation P28482 (MAPK1) HPRD 19413330, 17287340, 18767875, ...19651622, 11408587, 20068231
T415 Phosphorylation HPRD 19413330, 16964243, 19664994, ...19664995, 19651622, 18669648, 19415658, 20068231, 17081983
S432 Phosphorylation HPRD 18669648, 16964243, 20068231
T433 Phosphorylation HPRD 19413330, 19664994, 19664995, ...18452278, 18669648, 20068231
S436 Phosphorylation HPRD 18669648
S449 Phosphorylation HPRD 18669648, 20068231, 18452278
S451 Phosphorylation HPRD 19413330, 16964243, 19664994, ...19664995, 18452278, 19651622, 18669648, 19415658, 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047589 (hGORASP2/InitMet-/Phos:1) pT222,pT225 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S26 F26 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K212 R212 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S214 Y214 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc, tcga ]
S260 Y260 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T415 M415 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S432 F432 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ]