iPTMnet Report for Q9H8Y5 (ANKZF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H8Y5 / ANKZ1_HUMAN
Protein Name tRNA endonuclease ANKZF1
Gene Name Name: ANKZF1
Synonyms:ZNF744;
Organism Homo sapiens (Human)

PRO ID PR:Q9H8Y5
DAG View
PRO Name ankyrin repeat and zinc finger domain-containing protein 1 (human)
Definition An ankyrin repeat and zinc finger domain-containing protein 1 that is encoded in the genome of human.
Short Label hANKZF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H8Y5 (ANKZF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
T46 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
K101 Methylation PhosphoSitePlus
S119 Phosphorylation HPRD 17081983
S120 Phosphorylation HPRD 17081983
T121 Phosphorylation HPRD 17081983
S125 Phosphorylation HPRD 17081983
S126 Phosphorylation HPRD 17081983
S128 Phosphorylation HPRD 17081983
S133 Phosphorylation HPRD 17081983
Y176 Phosphorylation PhosphoSitePlus
C207 Methylation IEDB 31844290
R242 Methylation PhosphoSitePlus
R252 Methylation PhosphoSitePlus
S258 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231, 17924679
K273 Ubiquitination PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
S301 O-Glycosylation GlyGen 30379171, 28510447
K310 Acetylation PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
S361 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 23186163, 18767875, ...17322306, 20068231
T364 Phosphorylation PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
S398 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 16964243, ...20068231
K511 Ubiquitination PhosphoSitePlus
S533 Phosphorylation HPRD   PhosphoSitePlus   UniProt 17322306, 23186163, 20068231
T562 Phosphorylation HPRD 20068231
Y572 Phosphorylation PhosphoSitePlus
S579 Phosphorylation PhosphoSitePlus
T580 Phosphorylation PhosphoSitePlus
K599 Methylation PhosphoSitePlus
T607 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 16964243, ...15302935, 19664995, 18669648, 20068231
T674 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S675 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 18220336, ...15302935, 18669648, 20068231
S680 Phosphorylation PhosphoSitePlus   UniProt 23186163


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S15 P15 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S56 N56 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S120 F120 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S128 L128 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y176 S176 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S258 Y258 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S301 C301 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S301 F301 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K310 T310 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K367 E367 Biomuta DOID:3571 / liver cancer [ cosmic ]
S398 F398 Biomuta DOID:4159 / skin cancer [ cosmic ]
T674 A674 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]