iPTMnet Report for Q9H8X2 (IPPK)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H8X2 / IPPK_HUMAN
Protein Name Inositol-pentakisphosphate 2-kinase
Gene Name Name: IPPK
Synonyms:C9orf12;
Organism Homo sapiens (Human)

PRO ID PR:Q9H8X2
DAG View
PRO Name inositol-pentakisphosphate 2-kinase (human)
Definition An inositol-pentakisphosphate 2-kinase that is encoded in the genome of human.
Short Label hIPPK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H8X2 (IPPK) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C134 Methylation IEDB 31844290
K173 Ubiquitination PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K198 Methylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus   UniProt 23186163
K317 Ubiquitination PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
K479 Ubiquitination PhosphoSitePlus
K490 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K198 N198 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K198 R198 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S418 C418 Biomuta DOID:1319 / brain cancer [ cosmic ]