iPTMnet Report for Q9H8V3 (ECT2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H8V3 / ECT2_HUMAN
Protein Name Protein ECT2
Gene Name Name: ECT2
Organism Homo sapiens (Human)

PRO ID PR:Q9H8V3
DAG View
PRO Name protein ECT2 (human)
Definition A protein ECT2 that is encoded in the genome of human.
Short Label hECT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H8V3 (ECT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
S5 Phosphorylation PhosphoSitePlus
R13 Methylation PhosphoSitePlus
T14 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
K25 Sumoylation PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
S40 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
Y41 Phosphorylation phospho.ELM 18669648
K61 Ubiquitination PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
C157 Methylation IEDB 31844290
K213 Ubiquitination PhosphoSitePlus
K226 Acetylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
Y244 Phosphorylation PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
T359 Phosphorylation P41743 (PRKCI) IEDB   neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 21406692, 23186163, 30278072, ...27920218, 21189248, 20068231
K364 Ubiquitination PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S370 Phosphorylation PhosphoSitePlus   UniProt 18669648
T373 Phosphorylation P06493 (CDK1) neXtProt   PhosphoSitePlus   Signor   UniProt 18669648, 16247472, 16170345
S376 Phosphorylation PhosphoSitePlus   UniProt 18669648
K384 Ubiquitination PhosphoSitePlus
T386 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
T394 Phosphorylation PhosphoSitePlus
S397 Phosphorylation PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
S406 Phosphorylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
T422 Phosphorylation PhosphoSitePlus
T444 Phosphorylation P06493 (CDK1) neXtProt   PhosphoSitePlus   Signor   UniProt 16247472, 16170345
S448 Phosphorylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
K499 Ubiquitination PhosphoSitePlus
K516 Ubiquitination PhosphoSitePlus
K530 Ubiquitination PhosphoSitePlus
K538 Ubiquitination PhosphoSitePlus
Y539 Phosphorylation PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
K563 Sumoylation PhosphoSitePlus
S602 Phosphorylation PhosphoSitePlus
K611 Ubiquitination PhosphoSitePlus
K626 Ubiquitination PhosphoSitePlus
K632 Ubiquitination PhosphoSitePlus
K709 Ubiquitination PhosphoSitePlus
T713 Phosphorylation PhosphoSitePlus
S716 Phosphorylation PhosphoSitePlus   UniProt 23186163
K739 Ubiquitination PhosphoSitePlus
K797 Ubiquitination PhosphoSitePlus
S811 Phosphorylation phospho.ELM 18669648
K817 Ubiquitination PhosphoSitePlus
T838 Phosphorylation PhosphoSitePlus
S842 Phosphorylation PhosphoSitePlus   UniProt 18669648
S844 Phosphorylation PhosphoSitePlus
K845 Ubiquitination PhosphoSitePlus
T846 Phosphorylation P06493 (CDK1) neXtProt   PhosphoSitePlus   Signor   UniProt 18669648, 16247472, 16170345
T857 Phosphorylation PhosphoSitePlus
S858 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S861 Phosphorylation PhosphoSitePlus   UniProt 23186163
S866 Phosphorylation PhosphoSitePlus   UniProt 23186163
S879 O-Glycosylation GlyGen 30379171, 31492838, 35132862, ...30620550
S879 Phosphorylation PhosphoSitePlus
S880 Phosphorylation PhosphoSitePlus
T881 Phosphorylation PhosphoSitePlus
S882 Phosphorylation PhosphoSitePlus
S883 Phosphorylation PhosphoSitePlus
S889 Phosphorylation PhosphoSitePlus
S891 Phosphorylation PhosphoSitePlus
S894 O-Glycosylation GlyGen 30379171, 31492838, 35132862
S907 Phosphorylation PhosphoSitePlus
S909 Phosphorylation PhosphoSitePlus
T910 Phosphorylation PhosphoSitePlus
T911 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T327 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
T790 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K950 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S40 Phosphorylation HPRD 18669648
Y41 Phosphorylation HPRD 18669648
T328 Phosphorylation HPRD 20068231
S334 Phosphorylation HPRD 18669648
S336 Phosphorylation HPRD 18669648
S339 Phosphorylation HPRD 18669648
T342 Phosphorylation HPRD 18669648, 20068231
S345 Phosphorylation HPRD 18669648, 20068231
S685 Phosphorylation HPRD 20068231
S811 Phosphorylation HPRD 18669648
T815 Phosphorylation P53350 (PLK1) , P06493 (CDK1) HPRD 18669648, 16247472
S852 Phosphorylation HPRD 20068231
S858 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S19 C19 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S24 F24 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y41 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K299 T299 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T327 A327 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K327 N327 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
T328 A328 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T328 N328 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
T359 A359 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T359 N359 Biomuta DOID:1324 / lung cancer [ cosmic ]
S397 P397 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S406 L406 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S412 F412 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S420 A420 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S420 F420 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T444 I444 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T713 I713 Biomuta DOID:4159 / skin cancer [ cosmic ]
K739 T739 Biomuta DOID:1324 / lung cancer [ cosmic ]
S811 F811 Biomuta DOID:4159 / skin cancer [ cosmic ]
T815 I815 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ]
T846 I846 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ]
S861 L861 Biomuta DOID:1612 / breast cancer [ cosmic ]
S909 F909 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]