iPTMnet Report Q9H8S9 MOB1A

Protein Information

UniProt AC / UniProt ID	Q9H8S9 / MOB1A_HUMAN
Protein Name	MOB kinase activator 1A
Gene Name	Name: MOB1A Synonyms:C2orf6,MOB4B,MOBK1B,MOBKL1B;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9H8S9 DAG View
PRO Name	MOB kinase activator 1A (human)
Definition	A MOB kinase activator 1A that is encoded in the genome of human.
Short Label	hMOB1A
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9H8S9 (MOB1A) as Substrate

Condensed View

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position S2 S6 S9 S10 K11 T12 K16 K17 S23 Y26 K30 T35 S38 T74 Y95 K104 K142 K149 T181 S213	PTM Type Select all Acetylation Phosphorylation Ubiquitination	PTM Enzyme Select all Q13043 (STK4) Q13188 (STK3)	Score Select all 1 2 3 4	Source Select all PRO PhosphoSitePlus RLIMS-P Signor UniProt neXtProt phospho.ELM	PMID
S2	Acetylation		score1	UniProt	22814378, 12665801
S2	Phosphorylation		score1	PhosphoSitePlus
S6	Phosphorylation		score1	PhosphoSitePlus
S9	Phosphorylation		score1	PhosphoSitePlus
S10	Phosphorylation		score1	PhosphoSitePlus
K11	Acetylation		score1	PhosphoSitePlus
T12	Phosphorylation		score4	neXtProt PRO PhosphoSitePlus RLIMS-P Signor UniProt	18328708, 23431053, 21808241, ...19919647, 26108669
T12	Phosphorylation	Q13043 (STK4)	score4	neXtProt Signor	21808241, 18328708, 23431053
T12	Phosphorylation	Q13188 (STK3)	score4	PhosphoSitePlus Signor	21808241, 26108669, 23431053
K16	Acetylation		score1	PhosphoSitePlus
K17	Acetylation		score1	PhosphoSitePlus
K17	Ubiquitination		score1	PhosphoSitePlus
S23	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	17287340
Y26	Phosphorylation		score3	PhosphoSitePlus RLIMS-P	28675297
K30	Ubiquitination		score1	PhosphoSitePlus
T35	Phosphorylation		score4	neXtProt PRO PhosphoSitePlus RLIMS-P Signor UniProt	18328708, 23431053, 27555231, ...32973917, 21808241, 19919647, 26108669
T35	Phosphorylation	Q13043 (STK4)	score4	neXtProt Signor	21808241, 18328708, 23431053
T35	Phosphorylation	Q13188 (STK3)	score4	PhosphoSitePlus Signor	21808241, 26108669, 23431053
S38	Phosphorylation		score1	PhosphoSitePlus
T74	Phosphorylation		score3	PhosphoSitePlus RLIMS-P Signor UniProt	18362890
T74	Phosphorylation	Q13188 (STK3)	score3	PhosphoSitePlus Signor	18362890
Y95	Phosphorylation		score1	PhosphoSitePlus
K104	Acetylation		score1	PhosphoSitePlus
K142	Ubiquitination		score1	PhosphoSitePlus
K149	Acetylation		score1	PhosphoSitePlus
T181	Phosphorylation		score2	UniProt	18362890
S213	Phosphorylation		score1	PhosphoSitePlus

Search:

Site Select all By amino acid All Serine All Threonine By position S2 S23 T35 S38	PTM Type Select all Phosphorylation	Score Select all 0	Source Select all HPRD	PMID
S2	Phosphorylation	score0	HPRD	20068231
S23	Phosphorylation	score0	HPRD	17287340
T35	Phosphorylation	score0	HPRD	18691976, 18669648, 18212344, ...20068231
S38	Phosphorylation	score0	HPRD	20068231

Proteoforms

Search:

	PRO ID (Short Label) Select all PR:000048409 (hMOB1A/InitMet-/Phos:1)	Sites Select all pT12,pT35	PTM Enzyme Select all	Source Select all PRO	PMID
	PR:000048409 (hMOB1A/InitMet-/Phos:1)	pT12,pT35		PRO

PTM-dependent PPI

Search:

	PTM type Select all Phosphorylation	Substrate Select all Q9H8S9 (MOB1A)	Site Select all By amino acid All Threonine By position T12	Interactant Select all Q15208 (STK38)	Association type Select all unknown	Source Select all eFIP	PMID
	Phosphorylation	Q9H8S9 (MOB1A)	T12	Q15208 (STK38)	unknown	eFIP	27213455

PTM sites affected in variants

Search:

Site Select all By amino acid All Tyrosine By position K16 K17 Y95 K104	Variant Select all E104 F95 N16 R17	Source Select all Biomuta	Disease [Sample source] Select all DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K16	N16	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
K17	R17	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
Y95	F95	Biomuta	DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K104	E104	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for Q9H8S9 (MOB1A)

Protein Information

Interactive Sequence View

Q9H8S9 (MOB1A) as Substrate

Proteoforms

PTM-dependent PPI

PTM sites affected in variants