iPTMnet Report for Q9H8H2 (DDX31)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H8H2 / DDX31_HUMAN
Protein Name Probable ATP-dependent RNA helicase DDX31
Gene Name Name: DDX31
Organism Homo sapiens (Human)

PRO ID PR:Q9H8H2
DAG View
PRO Name probable ATP-dependent RNA helicase DDX31 (human)
Definition A probable ATP-dependent RNA helicase DDX31 that is encoded in the genome of human.
Short Label hDDX31
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H8H2 (DDX31) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S54 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
T363 Phosphorylation PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
K448 Ubiquitination PhosphoSitePlus
K456 Ubiquitination PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
K482 Ubiquitination PhosphoSitePlus
T568 Phosphorylation PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus
S737 Phosphorylation PhosphoSitePlus
S746 Phosphorylation PhosphoSitePlus
T760 Phosphorylation PhosphoSitePlus
S782 Phosphorylation PhosphoSitePlus
T823 Phosphorylation PhosphoSitePlus
R828 Methylation PhosphoSitePlus   UniProt 24129315
K830 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K281 R281 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S362 * Biomuta DOID:1612 / breast cancer [ cosmic ]
K372 N372 Biomuta DOID:1324 / lung cancer [ cosmic ]
K448 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K482 R482 Biomuta DOID:1324 / lung cancer [ cosmic ]
K482 N482 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S782 N782 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R828 H828 Biomuta DOID:363 / uterine cancer [ cosmic ]
R828 C828 Biomuta DOID:4606 / bile duct cancer [ cosmic ]