iPTMnet Report for Q9H8G2 (CAAP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H8G2 / CAAP1_HUMAN
Protein Name Caspase activity and apoptosis inhibitor 1
Gene Name Name: CAAP1
Synonyms:C9orf82,CAAP;
Organism Homo sapiens (Human)

PRO ID PR:Q9H8G2
DAG View
PRO Name caspase activity and apoptosis inhibitor 1 (human)
Definition A caspase activity and apoptosis inhibitor 1 that is encoded in the genome of human.
Short Label hCAAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H8G2 (CAAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S89 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T90 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S92 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S93 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S94 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S96 Phosphorylation PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus   UniProt 24275569
S187 Phosphorylation PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
S203 Phosphorylation O14757 (CHEK1) phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18318008, 18669648, 21851590, 24275569, 19690332, 20068231
S213 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
S221 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
C226 S-Nitrosylation dbSNO 26338901
S232 Phosphorylation PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
S311 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S312 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 15302935, ...18669648, 24275569, 19690332, 20068231
K349 Acetylation PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
K353 Acetylation PhosphoSitePlus
K359 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 20068231
S7 Phosphorylation HPRD 20068231
S89 Phosphorylation HPRD 19413330, 18691976, 18767875, ...19664995, 18452278, 19651622, 18669648, 20068231
T90 Phosphorylation HPRD 19413330, 18669648, 19664995, ...20068231, 18452278
S92 Phosphorylation HPRD 19413330, 18669648, 19664995
S93 Phosphorylation HPRD 18669648
S94 Phosphorylation HPRD 19413330, 18669648
S203 Phosphorylation HPRD 19413330, 17081983, 18767875, ...19664995, 18452278, 19651622, 18669648, 20068231
S221 Phosphorylation HPRD 17525332
S311 Phosphorylation HPRD 18669648, 19664995, 20068231
S312 Phosphorylation HPRD 19413330, 15302935, 19664994, ...19664995, 18452278, 19651622, 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S94 T94 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S96 L96 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S120 I120 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K189 N189 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S213 F213 Biomuta DOID:2531 / hematologic cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
C226 Y226 Biomuta DOID:1324 / lung cancer [ cosmic ]
S311 P311 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S312 R312 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S312 C312 Biomuta DOID:1612 / breast cancer [ icgc ]