iPTMnet Report for Q9H832 (UBE2Z)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H832 / UBE2Z_HUMAN
Protein Name Ubiquitin-conjugating enzyme E2 Z
Gene Name Name: UBE2Z
ORFNames:HOYS7;
Organism Homo sapiens (Human)

PRO ID PR:Q9H832
DAG View
PRO Name ubiquitin-conjugating enzyme E2 Z (human)
Definition A ubiquitin-conjugating enzyme E2 Z that is encoded in the genome of human.
Short Label hUBE2Z
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H832 (UBE2Z) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K113 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
R268 Methylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K304 Acetylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
S337 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S339 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S340 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S341 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T125 Phosphorylation HPRD 20068231
S337 Phosphorylation HPRD 19651622, 20068231
S339 Phosphorylation HPRD 19651622, 20068231
S340 Phosphorylation HPRD 19651622
S341 Phosphorylation HPRD 19651622
S342 Phosphorylation HPRD 19651622
T344 Phosphorylation HPRD 19651622
T346 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K113 T113 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T125 I125 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R268 Q268 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S340 I340 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S341 L341 Biomuta DOID:11054 / urinary bladder cancer [ icgc ]