iPTMnet Report for Q9H7Z7 (PTGES2)
Protein Information
UniProt AC / UniProt ID | Q9H7Z7 / PGES2_HUMAN |
Protein Name | Prostaglandin E synthase 2 |
Gene Name | Name: PTGES2 Synonyms:C9orf15,PGES2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H7Z7 |
PRO Name | prostaglandin E synthase 2 (human) |
Definition | A prostaglandin E synthase 2 that is encoded in the genome of human. |
Short Label | hPTGES2 |
Category | organism-gene |
Q9H7Z7 (PTGES2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S46 | Phosphorylation | score1 | PhosphoSitePlus | |||
K53 | Acetylation | score1 | PhosphoSitePlus | |||
T75 | Phosphorylation | score1 | PhosphoSitePlus | |||
S90 | Phosphorylation | score1 | PhosphoSitePlus | |||
S95 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 23186163, 20068231 | ||
S97 | Phosphorylation | score1 | PhosphoSitePlus | |||
T109 | Phosphorylation | score1 | PhosphoSitePlus | |||
K115 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y127 | Phosphorylation | score1 | PhosphoSitePlus | |||
K141 | Ubiquitination | score1 | PhosphoSitePlus | |||
K147 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y188 | Phosphorylation | score1 | PhosphoSitePlus | |||
K193 | Ubiquitination | score1 | PhosphoSitePlus | |||
K200 | Ubiquitination | score1 | PhosphoSitePlus | |||
T203 | Phosphorylation | score1 | PhosphoSitePlus | |||
K208 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y209 | Phosphorylation | score1 | PhosphoSitePlus | |||
K216 | Ubiquitination | score1 | PhosphoSitePlus | |||
K225 | Ubiquitination | score1 | PhosphoSitePlus | |||
K233 | Ubiquitination | score1 | PhosphoSitePlus | |||
S260 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y263 | Phosphorylation | score1 | PhosphoSitePlus | |||
K269 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y280 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y287 | Phosphorylation | score1 | PhosphoSitePlus | |||
S290 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y308 | Phosphorylation | score1 | PhosphoSitePlus | |||
K313 | Ubiquitination | score1 | PhosphoSitePlus | |||
T371 | Phosphorylation | score0 | HPRD | 20068231 | ||
S374 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S95 | Y95 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
K147 | M147 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K200 | N200 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y209 | S209 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
K225 | N225 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |