iPTMnet Report for Q9H7Z7 (PTGES2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H7Z7 / PGES2_HUMAN
Protein Name Prostaglandin E synthase 2
Gene Name Name: PTGES2
Synonyms:C9orf15,PGES2;
Organism Homo sapiens (Human)

PRO ID PR:Q9H7Z7
DAG View
PRO Name prostaglandin E synthase 2 (human)
Definition A prostaglandin E synthase 2 that is encoded in the genome of human.
Short Label hPTGES2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H7Z7 (PTGES2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S46 Phosphorylation PhosphoSitePlus
K53 Acetylation PhosphoSitePlus
T75 Phosphorylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
S95 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
S97 Phosphorylation PhosphoSitePlus
T109 Phosphorylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
Y127 Phosphorylation PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
Y188 Phosphorylation PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
T203 Phosphorylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
Y209 Phosphorylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
Y263 Phosphorylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
Y280 Phosphorylation PhosphoSitePlus
Y287 Phosphorylation PhosphoSitePlus
S290 Phosphorylation PhosphoSitePlus
Y308 Phosphorylation PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
T371 Phosphorylation HPRD 20068231
S374 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S95 Y95 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K147 M147 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K200 N200 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y209 S209 Biomuta DOID:363 / uterine cancer [ cosmic ]
K225 N225 Biomuta DOID:10534 / stomach cancer [ cosmic ]