iPTMnet Report for Q9H7Z6 (KAT8)
Protein Information
| UniProt AC / UniProt ID | Q9H7Z6 / KAT8_HUMAN |
| Protein Name | Histone acetyltransferase KAT8 |
| Gene Name | Name: KAT8 Synonyms:MOF,MYST1;ORFNames:PP7073; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H7Z6 |
| PRO Name | histone acetyltransferase KAT8 (human) |
| Definition | A histone acetyltransferase KAT8 that is encoded in the genome of human. |
| Short Label | hKAT8 |
| Category | organism-gene |
DAG ViewQ9H7Z6 (KAT8) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330, 22814378 | ||
| T14 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S15 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S37 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y90 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K106 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K113 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K113 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T114 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K116 | Acetylation | score1 | PhosphoSitePlus | |||
| K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K154 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K168 | Acetylation | score1 | PhosphoSitePlus | |||
| K168 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T174 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K175 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K177 | Acetylation | score1 | PhosphoSitePlus | |||
| K238 | Acetylation | score1 | PhosphoSitePlus | |||
| Y241 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K243 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K254 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K274 | Acetylation | Q9H7Z6 (KAT8) | score4 | PhosphoSitePlus UniProt | 21691301, 22020126, 21217699, ... | |
| S344 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S348 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K351 | Acetylation | score1 | PhosphoSitePlus | |||
| K351 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T392 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 24953651 | ||
| K410 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C416 | Methylation | score1 | IEDB | 31844290 | ||
| K427 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K433 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K444 | Ubiquitination | score1 | PhosphoSitePlus |
Q9H7Z6 (KAT8) as PTM Enzyme
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S37 | T37 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| Y90 | C90 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] | |
| K125 | R125 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
| K154 | R154 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K175 | E175 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K254 | E254 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| K274 | N274 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
| C416 | W416 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K433 | R433 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
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