iPTMnet Report for Q9H7Z3 (NRDE2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H7Z3 / NRDE2_HUMAN
Protein Name Nuclear exosome regulator NRDE2
Gene Name Name: NRDE2
Synonyms:C14orf102;
Organism Homo sapiens (Human)

PRO ID PR:Q9H7Z3
DAG View
PRO Name nuclear exosome regulator NRDE2 (human)
Definition A nuclear exosome regulator NRDE2 that is encoded in the genome of human.
Short Label hNRDE2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H7Z3 (NRDE2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 22223895
K62 Acetylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
K76 Acetylation PhosphoSitePlus
K97 Acetylation PhosphoSitePlus
K97 Methylation PhosphoSitePlus
K99 Methylation PhosphoSitePlus
K101 Methylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
T399 Phosphorylation PhosphoSitePlus
K443 Ubiquitination PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
K570 Ubiquitination PhosphoSitePlus
T573 Phosphorylation IEDB 35494241
K772 Ubiquitination PhosphoSitePlus
T805 Phosphorylation PhosphoSitePlus
K1029 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S63 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S66 L66 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S69 R69 Biomuta DOID:1324 / lung cancer [ cosmic ]
K443 T443 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]