iPTMnet Report for Q9H7D0 (DOCK5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H7D0 / DOCK5_HUMAN
Protein Name Dedicator of cytokinesis protein 5
Gene Name Name: DOCK5
Organism Homo sapiens (Human)

PRO ID PR:Q9H7D0
DAG View
PRO Name dedicator of cytokinesis protein 5 (human)
Definition A dedicator of cytokinesis protein 5 that is encoded in the genome of human.
Short Label hDOCK5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H7D0 (DOCK5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K53 Ubiquitination PhosphoSitePlus
Y106 Phosphorylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus   UniProt 18691976
T369 Phosphorylation PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
K415 Ubiquitination PhosphoSitePlus
K482 Ubiquitination PhosphoSitePlus
K497 Acetylation PhosphoSitePlus
K573 Ubiquitination PhosphoSitePlus
K604 Ubiquitination PhosphoSitePlus
T610 Phosphorylation PhosphoSitePlus
S619 Phosphorylation PhosphoSitePlus
T624 Phosphorylation PhosphoSitePlus
K651 Ubiquitination PhosphoSitePlus
K818 Acetylation PhosphoSitePlus   UniProt 19608861
K818 Ubiquitination PhosphoSitePlus
K856 Ubiquitination PhosphoSitePlus
K999 Ubiquitination PhosphoSitePlus
R1019 Methylation PhosphoSitePlus
K1169 Ubiquitination PhosphoSitePlus
S1198 Phosphorylation PhosphoSitePlus
S1222 Phosphorylation PhosphoSitePlus
T1224 Phosphorylation PhosphoSitePlus
K1246 Ubiquitination PhosphoSitePlus
S1287 Phosphorylation PhosphoSitePlus
Y1291 Phosphorylation PhosphoSitePlus
K1316 Ubiquitination PhosphoSitePlus
K1322 Ubiquitination PhosphoSitePlus
K1331 Ubiquitination PhosphoSitePlus
K1343 Ubiquitination PhosphoSitePlus
S1347 Phosphorylation PhosphoSitePlus
Y1349 Phosphorylation PhosphoSitePlus
S1395 Phosphorylation PhosphoSitePlus
K1407 Ubiquitination PhosphoSitePlus
K1444 Ubiquitination PhosphoSitePlus
K1574 Ubiquitination PhosphoSitePlus
K1585 Ubiquitination PhosphoSitePlus
T1601 Phosphorylation PhosphoSitePlus
K1616 Ubiquitination PhosphoSitePlus
Y1637 Phosphorylation PhosphoSitePlus
T1641 Phosphorylation PhosphoSitePlus
S1652 Phosphorylation PhosphoSitePlus
T1654 Phosphorylation PhosphoSitePlus
S1656 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y1661 Phosphorylation PhosphoSitePlus
S1671 Phosphorylation PhosphoSitePlus
T1673 Phosphorylation PhosphoSitePlus
S1687 Phosphorylation PhosphoSitePlus
S1719 Phosphorylation PhosphoSitePlus
S1725 Phosphorylation PhosphoSitePlus
S1738 Phosphorylation PhosphoSitePlus
S1740 Phosphorylation PhosphoSitePlus
K1741 Ubiquitination PhosphoSitePlus
S1742 Phosphorylation PhosphoSitePlus
S1756 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1758 Phosphorylation PhosphoSitePlus
S1766 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S1775 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1780 Phosphorylation phospho.ELM 18669648
S1781 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1785 Phosphorylation PhosphoSitePlus
T1786 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1789 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T1794 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T1800 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1802 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1803 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1805 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T1808 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T1814 Phosphorylation PhosphoSitePlus   UniProt 16964243
S1824 Phosphorylation PhosphoSitePlus
Y1827 Phosphorylation PhosphoSitePlus
S1830 Phosphorylation PhosphoSitePlus
S1834 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
T1835 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1860 O-Glycosylation GlyGen 35289036, 28657654, 30620550
S1860 Phosphorylation PhosphoSitePlus
T1864 Phosphorylation PhosphoSitePlus
S1865 O-Glycosylation GlyGen 35289036, 28657654, 30620550
S1869 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Site PTM Type PTM Enzyme Score Source PMID
T121 Phosphorylation HPRD 20068231
Y122 Phosphorylation HPRD 20068231
S133 Phosphorylation HPRD 20068231
T135 Phosphorylation HPRD 20068231
S365 Phosphorylation HPRD 18691976, 20068231
S1656 Phosphorylation HPRD 18669648
S1756 Phosphorylation HPRD 18691976, 20068231
S1766 Phosphorylation HPRD 19651622, 18669648, 18212344, ...20068231
S1775 Phosphorylation HPRD 18669648, 20068231
S1780 Phosphorylation HPRD 18669648, 20068231
S1781 Phosphorylation HPRD 18669648, 20068231
T1786 Phosphorylation HPRD 18669648
S1789 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231
T1794 Phosphorylation HPRD 19651622, 18669648
T1800 Phosphorylation HPRD 18691976, 18669648, 16964243
S1802 Phosphorylation HPRD 18669648
S1803 Phosphorylation HPRD 18669648, 16964243
S1805 Phosphorylation HPRD 18669648
T1808 Phosphorylation HPRD 18669648
T1814 Phosphorylation HPRD 16964243
S1834 Phosphorylation HPRD 19651622, 18691976, 18669648
T1835 Phosphorylation HPRD 18669648
S1869 Phosphorylation HPRD 18691976, 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T121 A121 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S133 P133 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S133 F133 Biomuta DOID:1324 / lung cancer [ cosmic ]
K151 T151 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K604 T604 Biomuta DOID:363 / uterine cancer [ icgc ]
S619 N619 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1019 C1019 Biomuta DOID:4159 / skin cancer [ cosmic ]
R1019 H1019 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S1222 N1222 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K1246 E1246 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K1343 N1343 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y1349 H1349 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1574 N1574 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
T1654 M1654 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic, icgc ]
S1656 T1656 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y1661 C1661 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S1756 N1756 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S1766 N1766 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1781 L1781 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1803 P1803 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y1827 H1827 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1830 R1830 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1834 C1834 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]