iPTMnet Report for Q9H7B2 (RPF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H7B2 / RPF2_HUMAN
Protein Name Ribosome production factor 2 homolog
Gene Name Name: RPF2
Synonyms:BXDC1;
Organism Homo sapiens (Human)

PRO ID PR:Q9H7B2
DAG View
PRO Name ribosome production factor 2 homolog (human)
Definition A ribosome production factor 2 homolog that is encoded in the genome of human.
Short Label hRPF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H7B2 (RPF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R6 Methylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
K47 Acetylation PhosphoSitePlus
K56 Acetylation PhosphoSitePlus
Y59 Phosphorylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
S85 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
Y109 Phosphorylation PhosphoSitePlus
Y156 Phosphorylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
S161 Phosphorylation PhosphoSitePlus
Y194 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus
Y236 Phosphorylation PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
Y263 Phosphorylation PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K31 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K83 N83 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S94 C94 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y109 H109 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S161 G161 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y194 C194 Biomuta DOID:5158 / pleural cancer [ cosmic ]
K252 N252 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ]
S255 F255 Biomuta DOID:4159 / skin cancer [ cosmic ]