iPTMnet Report for Q9H706 (GAREM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H706 / GARE1_HUMAN
Protein Name GRB2-associated and regulator of MAPK protein 1
Gene Name Name: GAREM1
Synonyms:C18orf11,FAM59A,GAREM;
Organism Homo sapiens (Human)

PRO ID PR:Q9H706
DAG View
PRO Name GRB2-associated and regulator of MAPK protein 1 (human)
Definition A GRB2-associated and regulator of MAPK protein 1 that is encoded in the genome of human.
Short Label hGAREM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H706 (GAREM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y52 Phosphorylation PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
Y74 Phosphorylation PhosphoSitePlus
Y105 Phosphorylation PhosphoSitePlus   UniProt 19509291
Y164 Phosphorylation PhosphoSitePlus
T167 Phosphorylation PhosphoSitePlus
T243 Phosphorylation PhosphoSitePlus
T250 Phosphorylation PhosphoSitePlus
Y260 Phosphorylation PhosphoSitePlus
Y271 Phosphorylation PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
S382 Phosphorylation PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus
Y453 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 15951569, 23882028, 19509291
S473 Phosphorylation PhosphoSitePlus
S484 Phosphorylation PhosphoSitePlus
S546 Phosphorylation PhosphoSitePlus
S563 Phosphorylation PhosphoSitePlus
S565 Phosphorylation PhosphoSitePlus
T567 Phosphorylation PhosphoSitePlus
S605 Phosphorylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus   UniProt 23186163
S614 Phosphorylation PhosphoSitePlus   UniProt 23186163
S625 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S647 Phosphorylation PhosphoSitePlus
S649 Phosphorylation PhosphoSitePlus
Y650 Phosphorylation PhosphoSitePlus
S651 Phosphorylation PhosphoSitePlus
T657 Phosphorylation PhosphoSitePlus
T660 Phosphorylation PhosphoSitePlus
S698 Phosphorylation PhosphoSitePlus
S700 Phosphorylation PhosphoSitePlus
Y701 Phosphorylation PhosphoSitePlus
S702 Phosphorylation PhosphoSitePlus
S742 Phosphorylation PhosphoSitePlus
S757 Phosphorylation PhosphoSitePlus
S759 Phosphorylation PhosphoSitePlus
Y767 Phosphorylation PhosphoSitePlus
S780 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y453 Phosphorylation HPRD   PhosphoSitePlus 17016520, 17389395, 15951569
S563 Phosphorylation PhosphoSitePlus
S565 Phosphorylation PhosphoSitePlus
Y570 Phosphorylation PhosphoSitePlus
Y571 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y105 H105 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y164 C164 Biomuta DOID:4159 / skin cancer [ cosmic ]
S382 F382 Biomuta DOID:4159 / skin cancer [ cosmic ]
S399 R399 Biomuta DOID:1324 / lung cancer [ cosmic ]
S563 Y563 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S565 G565 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T567 P567 Biomuta DOID:1612 / breast cancer [ cosmic ]
Y571 C571 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S605 Y605 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S610 F610 Biomuta DOID:4159 / skin cancer [ cosmic ]
S614 C614 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y650 F650 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S742 Y742 Biomuta DOID:363 / uterine cancer [ icgc, cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]