Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H6Z9 / EGLN3_HUMAN
Protein Name Prolyl hydroxylase EGLN3
Gene Name Name: EGLN3
Organism Homo sapiens (Human)

PRO ID PR:Q9H6Z9
DAG View
PRO Name prolyl hydroxylase EGLN3 (human)
Definition A prolyl hydroxylase EGLN3 that is encoded in the genome of human.
Short Label hEGLN3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H6Z9 (EGLN3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K48 Ubiquitination PhosphoSitePlus
T130 Phosphorylation PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
Y206 Phosphorylation PhosphoSitePlus
T209 Phosphorylation PhosphoSitePlus
Y212 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P14618 (PKM) S37 Q9H6Z9 (EGLN3) unknown eFIP 33637716


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K172 E172 Biomuta DOID:363 / uterine cancer [ icgc ]