iPTMnet Report for Q9H6Y7 (RNF167)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H6Y7 / RN167_HUMAN
Protein Name E3 ubiquitin-protein ligase RNF167 precursor
Gene Name Name: RNF167
Synonyms:RING105;ORFNames:LP2254;
Organism Homo sapiens (Human)

PRO ID PR:Q9H6Y7
DAG View
PRO Name E3 ubiquitin-protein ligase RNF167 (human)
Definition An E3 ubiquitin-protein ligase RNF167 that is encoded in the genome of human.
Short Label hRNF167
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H6Y7 (RNF167) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N33 N-Glycosylation GlyGen   UniProt 23129617
N79 N-Glycosylation GlyGen   UniProt 23129617
C92 Methylation IEDB 31844290
K97 Ubiquitination PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
Y237 Phosphorylation PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
C248 Methylation IEDB 31844290
K266 Ubiquitination PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
R277 Methylation PhosphoSitePlus
T288 Phosphorylation PhosphoSitePlus
T308 Phosphorylation IEDB 34433824
S341 Phosphorylation PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S313 Phosphorylation HPRD 20068231
S314 Phosphorylation HPRD 20068231
S335 Phosphorylation HPRD 20068231
T336 Phosphorylation HPRD 20068231
S341 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N79 S79 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K97 N97 Biomuta DOID:263 / kidney cancer [ cosmic ]
K272 N272 Biomuta DOID:363 / uterine cancer [ icgc ]
R277 W277 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R277 L277 Biomuta DOID:1324 / lung cancer [ cosmic ]
S341 P341 Biomuta DOID:263 / kidney cancer [ cosmic ]