iPTMnet Report for Q9H6T3 (RPAP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H6T3 / RPAP3_HUMAN
Protein Name RNA polymerase II-associated protein 3
Gene Name Name: RPAP3
Organism Homo sapiens (Human)

PRO ID PR:Q9H6T3
DAG View
PRO Name RNA polymerase II-associated protein 3 (human)
Definition An RNA polymerase II-associated protein 3 that is encoded in the genome of human.
Short Label hRPAP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H6T3 (RPAP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Acetylation UniProt 22814378
K33 Ubiquitination PhosphoSitePlus
T81 Phosphorylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
S87 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y88 Phosphorylation PhosphoSitePlus
Y90 Phosphorylation PhosphoSitePlus
S110 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T111 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S114 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S116 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
S119 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 24275569
S121 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
Y149 Phosphorylation PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
Y165 Phosphorylation PhosphoSitePlus
Y177 Phosphorylation PhosphoSitePlus
R198 Methylation PhosphoSitePlus
K216 Acetylation PhosphoSitePlus
Y224 Phosphorylation PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
K271 Acetylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
C304 Methylation IEDB 31844290
R307 Methylation PhosphoSitePlus
Y326 Phosphorylation PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
S480 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S481 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T488 Phosphorylation PhosphoSitePlus
S489 Phosphorylation PhosphoSitePlus
T491 Phosphorylation PhosphoSitePlus
K498 Sumoylation PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus
Y567 Phosphorylation PhosphoSitePlus
K607 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S87 Phosphorylation HPRD 18669648
S110 Phosphorylation HPRD 18669648, 17081983, 20068231
T111 Phosphorylation HPRD 18669648, 17081983
S114 Phosphorylation HPRD 17081983
S116 Phosphorylation HPRD 17081983, 18077418, 18452278, ...19651622, 18669648, 20068231
S119 Phosphorylation HPRD 17081983, 18077418, 18452278, ...19651622, 18669648, 20068231
S121 Phosphorylation HPRD 17081983, 18077418, 18452278, ...19651622, 18669648, 20068231
S480 Phosphorylation HPRD 18669648, 20068231
S481 Phosphorylation HPRD 19651622, 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S87 C87 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y88 H88 Biomuta DOID:1324 / lung cancer [ cosmic ]
T111 I111 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S121 A121 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
R198 I198 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C304 W304 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y326 C326 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y326 H326 Biomuta DOID:4159 / skin cancer [ cosmic ]
S480 A480 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S480 L480 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]