iPTMnet Report Q9H6T3 RPAP3

Protein Information

UniProt AC / UniProt ID	Q9H6T3 / RPAP3_HUMAN
Protein Name	RNA polymerase II-associated protein 3
Gene Name	Name: RPAP3
Organism	Homo sapiens (Human)

PRO ID	PR:Q9H6T3 DAG View
PRO Name	RNA polymerase II-associated protein 3 (human)
Definition	An RNA polymerase II-associated protein 3 that is encoded in the genome of human.
Short Label	hRPAP3
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9H6T3 (RPAP3) as Substrate

Expanded View

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position T2 K33 T81 K86 S87 Y88 Y90 S110 T111 S114 S116 S119 S121 Y149 K158 Y165 Y177 R198 K216 Y224 K243 K251 K271 S284 C304 R307 Y326 K370 S391 S480 S481 T488 S489 T491 K498 S513 Y567 K607	PTM Type Select all Acetylation Methylation Phosphorylation Sumoylation Ubiquitination	Score Select all 1 2	Source Select all IEDB PhosphoSitePlus UniProt phospho.ELM	PMID
T2	Acetylation	score1	UniProt	22814378
K33	Ubiquitination	score1	PhosphoSitePlus
T81	Phosphorylation	score1	PhosphoSitePlus
K86	Ubiquitination	score1	PhosphoSitePlus
S87	Phosphorylation	score2	phospho.ELM PhosphoSitePlus UniProt	18669648
Y88	Phosphorylation	score1	PhosphoSitePlus
Y90	Phosphorylation	score1	PhosphoSitePlus
S110	Phosphorylation	score2	phospho.ELM PhosphoSitePlus	18669648
T111	Phosphorylation	score2	phospho.ELM PhosphoSitePlus	18669648
S114	Phosphorylation	score2	phospho.ELM PhosphoSitePlus	18669648
S116	Phosphorylation	score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 21406692
S119	Phosphorylation	score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 21406692, 24275569
S121	Phosphorylation	score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 21406692
Y149	Phosphorylation	score1	PhosphoSitePlus
K158	Ubiquitination	score1	PhosphoSitePlus
Y165	Phosphorylation	score1	PhosphoSitePlus
Y177	Phosphorylation	score1	PhosphoSitePlus
R198	Methylation	score1	PhosphoSitePlus
K216	Acetylation	score1	PhosphoSitePlus
Y224	Phosphorylation	score1	PhosphoSitePlus
K243	Ubiquitination	score1	PhosphoSitePlus
K251	Ubiquitination	score1	PhosphoSitePlus
K271	Acetylation	score1	PhosphoSitePlus
S284	Phosphorylation	score1	PhosphoSitePlus
C304	Methylation	score1	IEDB	31844290
R307	Methylation	score1	PhosphoSitePlus
Y326	Phosphorylation	score1	PhosphoSitePlus
K370	Ubiquitination	score1	PhosphoSitePlus
S391	Phosphorylation	score1	PhosphoSitePlus
S480	Phosphorylation	score2	phospho.ELM PhosphoSitePlus	18669648
S481	Phosphorylation	score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 23186163
T488	Phosphorylation	score1	PhosphoSitePlus
S489	Phosphorylation	score1	PhosphoSitePlus
T491	Phosphorylation	score1	PhosphoSitePlus
K498	Sumoylation	score1	PhosphoSitePlus
S513	Phosphorylation	score1	PhosphoSitePlus
Y567	Phosphorylation	score1	PhosphoSitePlus
K607	Acetylation	score1	PhosphoSitePlus

Search:

Site Select all By amino acid All Serine All Threonine By position S87 S110 T111 S114 S116 S119 S121 S480 S481	PTM Type Select all Phosphorylation	Score Select all 0	Source Select all HPRD	PMID
S87	Phosphorylation	score0	HPRD	18669648
S110	Phosphorylation	score0	HPRD	18669648, 17081983, 20068231
T111	Phosphorylation	score0	HPRD	18669648, 17081983
S114	Phosphorylation	score0	HPRD	17081983
S116	Phosphorylation	score0	HPRD	17081983, 18077418, 18452278, ...19651622, 18669648, 20068231
S119	Phosphorylation	score0	HPRD	17081983, 18077418, 18452278, ...19651622, 18669648, 20068231
S121	Phosphorylation	score0	HPRD	17081983, 18077418, 18452278, ...19651622, 18669648, 20068231
S480	Phosphorylation	score0	HPRD	18669648, 20068231
S481	Phosphorylation	score0	HPRD	19651622, 18669648, 20068231

PTM sites affected in variants

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position S87 Y88 T111 S121 R198 C304 Y326 S480	Variant Select all A121 A480 C326 C87 H326 H88 I111 I198 L480 W304	Source Select all Biomuta	Disease [Sample source] Select all DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ] [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S87	C87	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
Y88	H88	Biomuta	DOID:1324 / lung cancer [ cosmic ]
T111	I111	Biomuta	DOID:4159 / skin cancer [ cosmic, icgc ]
S121	A121	Biomuta	DOID:2394 / ovarian cancer [ cosmic, icgc ]
R198	I198	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
C304	W304	Biomuta	DOID:1324 / lung cancer [ cosmic ]
Y326	C326	Biomuta	DOID:2531 / hematologic cancer [ cosmic ]
Y326	H326	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S480	A480	Biomuta	[ cosmic ] DOID:1115 / sarcoma [ icgc ]
S480	L480	Biomuta	DOID:4159 / skin cancer [ cosmic, icgc ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for Q9H6T3 (RPAP3)

Protein Information

Interactive Sequence View

Q9H6T3 (RPAP3) as Substrate

PTM sites affected in variants