iPTMnet Report for Q9H6R3 (ACSS3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H6R3 / ACSS3_HUMAN
Protein Name Acyl-CoA synthetase short-chain family member 3, mitochondrial precursor
Gene Name Name: ACSS3
Organism Homo sapiens (Human)

PRO ID PR:Q9H6R3
DAG View
PRO Name acyl-CoA synthetase short-chain family member 3, mitochondrial (human)
Definition An acyl-CoA synthetase short-chain family member 3, mitochondrial that is encoded in the genome of human.
Short Label hACSS3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H6R3 (ACSS3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 O-Glycosylation GlyGen 30379171
S60 Phosphorylation PhosphoSitePlus
Y62 Phosphorylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
Y234 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
K524 Acetylation PhosphoSitePlus
S574 Phosphorylation PhosphoSitePlus
S656 Phosphorylation PhosphoSitePlus
Y664 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S196 R196 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S204 Y204 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S209 I209 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y234 C234 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y234 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K524 N524 Biomuta DOID:3571 / liver cancer [ cosmic ]
S574 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S656 F656 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y664 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y664 F664 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]