iPTMnet Report for Q9H6Q4 (CIAO3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H6Q4 / CIAO3_HUMAN
Protein Name Cytosolic iron-sulfur assembly component 3
Gene Name Name: CIAO3
Synonyms:NARFL;
Organism Homo sapiens (Human)

PRO ID PR:Q9H6Q4
DAG View
PRO Name cytosolic iron-sulfur assembly component 3 (human)
Definition A cytosolic iron-sulfur assembly component 3 that is encoded in the genome of human.
Short Label hCIAO3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H6Q4 (CIAO3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 20068231
S3 Phosphorylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
Y49 Phosphorylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
S107 O-Glycosylation GlyGen 30379171
K138 Ubiquitination PhosphoSitePlus
T140 O-Glycosylation GlyGen 30379171
S214 Phosphorylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
Y239 Phosphorylation PhosphoSitePlus
T242 Phosphorylation PhosphoSitePlus
Y247 Phosphorylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
C385 Methylation IEDB 31844290
S413 Phosphorylation PhosphoSitePlus
Y462 Phosphorylation IEDB   PhosphoSitePlus 35494241
K467 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation HPRD 20068231
Y49 Phosphorylation HPRD 15592455


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 L3 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
Y49 F49 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K102 N102 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K224 N224 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K237 E237 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K250 N250 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
C385 Y385 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y462 H462 Biomuta DOID:9256 / colorectal cancer [ cosmic ]