iPTMnet Report for Q9H6L5 (RETREG1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H6L5 / RETR1_HUMAN
Protein Name Reticulophagy regulator 1
Gene Name Name: RETREG1
Synonyms:FAM134B,JK1;
Organism Homo sapiens (Human)

PRO ID PR:Q9H6L5
DAG View
PRO Name reticulophagy regulator 1 (human)
Definition A reticulophagy regulator 1 that is encoded in the genome of human.
Short Label hRETREG1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H6L5 (RETREG1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation PhosphoSitePlus
S149 Phosphorylation UniProt 31930741
S151 Phosphorylation PhosphoSitePlus   UniProt 31930741
S153 Phosphorylation UniProt 31930741
K160 Acetylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
Y325 Phosphorylation PhosphoSitePlus
T326 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus
T359 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
S486 Phosphorylation PhosphoSitePlus
S487 Phosphorylation PhosphoSitePlus
S491 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S151 C151 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K247 R247 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S286 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S322 P322 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S322 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S344 F344 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S348 * Biomuta DOID:4362 / cervical cancer [ cosmic ]
S487 L487 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]