iPTMnet Report for Q9H6E5 (TUT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H6E5 / STPAP_HUMAN
Protein Name Speckle targeted PIP5K1A-regulated poly(A) polymerase
Gene Name Name: TUT1
Synonyms:RBM21;
Organism Homo sapiens (Human)

PRO ID PR:Q9H6E5
DAG View
PRO Name speckle targeted PIP5K1A-regulated poly(A) polymerase (human)
Definition A speckle targeted PIP5K1A-regulated poly(A) polymerase that is encoded in the genome of human.
Short Label hTUT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H6E5 (TUT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus   RLIMS-P   Signor 26138484, 29203642
S10 Phosphorylation PhosphoSitePlus
R13 Methylation PhosphoSitePlus
S112 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S133 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus
T329 Phosphorylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
S376 Phosphorylation PhosphoSitePlus
S423 Phosphorylation PhosphoSitePlus
Y573 Phosphorylation RLIMS-P 29203642
S644 Phosphorylation PhosphoSitePlus
T649 Phosphorylation PhosphoSitePlus
S652 Phosphorylation PhosphoSitePlus
S653 Phosphorylation PhosphoSitePlus
S658 Phosphorylation PhosphoSitePlus
K659 Acetylation PhosphoSitePlus
K741 Ubiquitination PhosphoSitePlus
S750 Phosphorylation Q13535 (ATR) PhosphoSitePlus 18077418
K790 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S6 L6 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S138 F138 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]