iPTMnet Report for Q9H694 (BICC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H694 / BICC1_HUMAN
Protein Name Protein bicaudal C homolog 1
Gene Name Name: BICC1
Organism Homo sapiens (Human)

PRO ID PR:Q9H694
DAG View
PRO Name protein bicaudal C homolog 1 (human)
Definition A protein bicaudal C homolog 1 that is encoded in the genome of human.
Short Label hBICC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H694 (BICC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
Y333 Phosphorylation PhosphoSitePlus
S394 O-Glycosylation GlyGen 30379171, 35254053
K398 Acetylation PhosphoSitePlus   UniProt 19608861
K398 Ubiquitination PhosphoSitePlus
S576 Phosphorylation PhosphoSitePlus   UniProt 20068231
K592 Ubiquitination PhosphoSitePlus
S612 Phosphorylation PhosphoSitePlus
S633 Phosphorylation PhosphoSitePlus
S635 Phosphorylation PhosphoSitePlus
S637 Phosphorylation PhosphoSitePlus
K667 Ubiquitination PhosphoSitePlus
S679 Phosphorylation PhosphoSitePlus
K693 Ubiquitination PhosphoSitePlus
S722 Phosphorylation PhosphoSitePlus
Y723 Phosphorylation PhosphoSitePlus
K734 Ubiquitination PhosphoSitePlus
T749 O-Glycosylation GlyGen 30379171, 35254053
K765 Ubiquitination PhosphoSitePlus
S766 Phosphorylation PhosphoSitePlus
S799 Phosphorylation PhosphoSitePlus
S803 Phosphorylation PhosphoSitePlus
S836 Phosphorylation PhosphoSitePlus
C857 Methylation IEDB 31844290
S943 Phosphorylation PhosphoSitePlus
S956 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S576 Phosphorylation HPRD 20068231
S633 Phosphorylation HPRD 19651622, 20068231
S836 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S576 P576 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S612 F612 Biomuta DOID:4159 / skin cancer [ cosmic ]
S633 R633 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S637 F637 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S679 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K693 T693 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T749 M749 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ]
S799 L799 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S803 N803 Biomuta DOID:4159 / skin cancer [ cosmic ]
S943 P943 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ]