iPTMnet Report for Q9H5Z1 (DHX35)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H5Z1 / DHX35_HUMAN
Protein Name Probable ATP-dependent RNA helicase DHX35
Gene Name Name: DHX35
Synonyms:C20orf15,DDX35;
Organism Homo sapiens (Human)

PRO ID PR:Q9H5Z1
DAG View
PRO Name probable ATP-dependent RNA helicase DHX35 (human)
Definition A probable ATP-dependent RNA helicase DHX35 that is encoded in the genome of human.
Short Label hDHX35
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H5Z1 (DHX35) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K9 Ubiquitination PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
Y249 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
Y257 Phosphorylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
Y356 Phosphorylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
T476 Phosphorylation PhosphoSitePlus
K537 Ubiquitination PhosphoSitePlus
K563 Ubiquitination PhosphoSitePlus
K573 Ubiquitination PhosphoSitePlus
K591 Ubiquitination PhosphoSitePlus
K597 Ubiquitination PhosphoSitePlus
Y627 Phosphorylation PhosphoSitePlus
K648 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y249 I249 Biomuta DOID:263 / kidney cancer [ cosmic ]
Y249 N249 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y249 F249 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K326 N326 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K648 R648 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]