iPTMnet Report for Q9H5N1 (RABEP2)
Protein Information
| UniProt AC / UniProt ID | Q9H5N1 / RABE2_HUMAN |
| Protein Name | Rab GTPase-binding effector protein 2 |
| Gene Name | Name: RABEP2 Synonyms:RABPT5B; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H5N1 |
| PRO Name | Rab GTPase-binding effector protein 2 (human) |
| Definition | A Rab GTPase-binding effector protein 2 that is encoded in the genome of human. |
| Short Label | hRABEP2 |
| Category | organism-gene |
Q9H5N1 (RABEP2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22814378 | ||
| S27 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S93 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K105 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K126 | Acetylation | score1 | PhosphoSitePlus | |||
| K126 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K161 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S189 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S193 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T194 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S200 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P UniProt | 29247183 | ||
| S204 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P UniProt | 29247183 | ||
| S257 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K497 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S27 | T27 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| S93 | P93 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S189 | F189 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T194 | M194 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| S204 | L204 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S257 | I257 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
DAG View