iPTMnet Report for Q9H568 (ACTL8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H568 / ACTL8_HUMAN
Protein Name Actin-like protein 8
Gene Name Name: ACTL8
Organism Homo sapiens (Human)

PRO ID PR:Q9H568
DAG View
PRO Name actin-like protein 8 (human)
Definition An actin-like protein 8 that is encoded in the genome of human.
Short Label hACTL8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H568 (ACTL8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T19 Phosphorylation HPRD 20068231
K39 Ubiquitination PhosphoSitePlus
S52 Phosphorylation HPRD   PhosphoSitePlus 20068231
T62 Phosphorylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
Y238 Phosphorylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
R357 Methylation PhosphoSitePlus
R365 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T19 P19 Biomuta DOID:1324 / lung cancer [ cosmic ]
K39 E39 Biomuta DOID:3571 / liver cancer [ cosmic ]
K186 N186 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y238 C238 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S244 F244 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ]
R357 Q357 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
R357 P357 Biomuta DOID:1612 / breast cancer [ cosmic ]