iPTMnet Report for Q9H553 (ALG2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H553 / ALG2_HUMAN
Protein Name Alpha-1,3/1,6-mannosyltransferase ALG2
Gene Name Name: ALG2
ORFNames:UNQ666/PRO1298;
Organism Homo sapiens (Human)

PRO ID PR:Q9H553
DAG View
PRO Name alpha-1,3/1,6-mannosyltransferase ALG2 (human)
Definition An alpha-1,3/1,6-mannosyltransferase ALG2 that is encoded in the genome of human.
Short Label hALG2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H553 (ALG2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K14 Ubiquitination PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
Y281 Phosphorylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
K383 Methylation PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus
Y410 Phosphorylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K215 R215 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y281 H281 Biomuta DOID:3571 / liver cancer [ cosmic ]
S381 F381 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K397 E397 Biomuta DOID:2531 / hematologic cancer [ cosmic ]