iPTMnet Report for Q9H4M9 (EHD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H4M9 / EHD1_HUMAN
Protein Name EH domain-containing protein 1
Gene Name Name: EHD1
Synonyms:PAST;ORFNames:CDABP0131;
Organism Homo sapiens (Human)

PRO ID PR:Q9H4M9
DAG View
PRO Name EH domain-containing protein 1 (human)
Definition An EH domain-containing protein 1 that is encoded in the genome of human.
Short Label hEHD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H4M9 (EHD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
K7 Ubiquitination PhosphoSitePlus
K13 Ubiquitination PhosphoSitePlus
Y29 Phosphorylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
Y40 Phosphorylation PhosphoSitePlus
T69 Phosphorylation PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
K208 Sumoylation PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
T226 Phosphorylation PhosphoSitePlus
T246 Phosphorylation HPRD 20068231
K280 Ubiquitination PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K324 Acetylation PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
K327 Acetylation PhosphoSitePlus
Y339 Phosphorylation PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K358 Ubiquitination PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
T417 Phosphorylation PhosphoSitePlus
Y426 Phosphorylation PhosphoSitePlus
T447 Phosphorylation PhosphoSitePlus
Y448 Phosphorylation PhosphoSitePlus
Y453 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15592455
T454 Phosphorylation HPRD   PhosphoSitePlus 18691976
S456 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 18452278, 19651622, 17322306, 18669648, 19690332, 20068231
K475 Ubiquitination PhosphoSitePlus
T479 Phosphorylation PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
K509 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K13 Q13 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K32 E32 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K32 M32 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y40 C40 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y40 S40 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T69 M69 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T226 M226 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
K293 N293 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S355 N355 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y426 H426 Biomuta DOID:3571 / liver cancer [ cosmic ]
S456 F456 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T479 I479 Biomuta DOID:4159 / skin cancer [ cosmic ]