iPTMnet Report for Q9H4M7 (PLEKHA4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H4M7 / PKHA4_HUMAN
Protein Name Pleckstrin homology domain-containing family A member 4
Gene Name Name: PLEKHA4
Synonyms:PEPP1;
Organism Homo sapiens (Human)

PRO ID PR:Q9H4M7
DAG View
PRO Name pleckstrin homology domain-containing family A member 4 (human)
Definition A pleckstrin homology domain-containing family A member 4 that is encoded in the genome of human.
Short Label hPLEKHA4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H4M7 (PLEKHA4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
Y159 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus   UniProt 24275569
S192 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
T211 Phosphorylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
T215 Phosphorylation PhosphoSitePlus
S229 Phosphorylation PhosphoSitePlus
T234 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
T271 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
R279 Methylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
T296 Phosphorylation PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
Y332 Phosphorylation PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
S559 Phosphorylation PhosphoSitePlus   UniProt 23186163
S575 Phosphorylation PhosphoSitePlus
T612 Phosphorylation PhosphoSitePlus
S613 Phosphorylation IEDB   PhosphoSitePlus 27869121
S624 Phosphorylation PhosphoSitePlus
S650 Phosphorylation PhosphoSitePlus
S675 Phosphorylation PhosphoSitePlus
S723 Phosphorylation PhosphoSitePlus
S778 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S557 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S20 Y20 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:3277 / thymus cancer [ cosmic ]
S21 L21 Biomuta DOID:363 / uterine cancer [ icgc ]
S194 L194 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T271 I271 Biomuta DOID:363 / uterine cancer [ icgc ]
R279 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
S292 F292 Biomuta DOID:4159 / skin cancer [ cosmic ]
T296 I296 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S345 F345 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S570 L570 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S575 F575 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S580 R580 Biomuta DOID:3571 / liver cancer [ cosmic ]
S613 F613 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S650 F650 Biomuta DOID:4159 / skin cancer [ cosmic ]
S723 F723 Biomuta DOID:4159 / skin cancer [ cosmic ]