iPTMnet Report for Q9H4G0 (EPB41L1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H4G0 / E41L1_HUMAN
Protein Name Band 4.1-like protein 1
Gene Name Name: EPB41L1
Synonyms:KIAA0338;
Organism Homo sapiens (Human)

PRO ID PR:Q9H4G0
DAG View
PRO Name band 4.1-like protein 1 (human)
Definition A band 4.1-like protein 1 that is encoded in the genome of human.
Short Label hEPB41L1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H4G0 (EPB41L1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S9 Phosphorylation PhosphoSitePlus
T30 Phosphorylation PhosphoSitePlus
T33 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
Y68 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
S75 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T78 Phosphorylation PhosphoSitePlus
T79 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S86 Phosphorylation PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
T102 Phosphorylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
Y109 Phosphorylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
T202 Phosphorylation PhosphoSitePlus
Y261 Phosphorylation PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
Y343 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
T349 Phosphorylation PhosphoSitePlus
S378 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243
S391 Phosphorylation PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus
S430 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 20068231
S437 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
S441 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983, 18220336
S443 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S461 Phosphorylation PhosphoSitePlus   UniProt 24275569
S466 Phosphorylation PhosphoSitePlus
T475 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T477 Phosphorylation PhosphoSitePlus
T489 Phosphorylation PhosphoSitePlus
K499 Ubiquitination PhosphoSitePlus
K506 Methylation PhosphoSitePlus
K506 Ubiquitination PhosphoSitePlus
S510 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
K515 Methylation PhosphoSitePlus
K515 Ubiquitination PhosphoSitePlus
S523 O-Glycosylation GlyGen 30379171, 32574038, 31492838, ...29351928, 35132862, 35254053, 28657654, 29237092, 30059200
S540 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S541 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S544 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...20068231
S546 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...20068231
T550 Phosphorylation PhosphoSitePlus   UniProt 23186163
S564 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 20068231
S578 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
T580 Phosphorylation PhosphoSitePlus
T591 Phosphorylation PhosphoSitePlus
K595 Ubiquitination PhosphoSitePlus
Y628 Phosphorylation PhosphoSitePlus
S639 Phosphorylation PhosphoSitePlus
S648 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...18220336
S650 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18220336, ...18669648, 20068231
T652 Phosphorylation PhosphoSitePlus
S658 Phosphorylation PhosphoSitePlus
K663 Ubiquitination PhosphoSitePlus
S667 Phosphorylation PhosphoSitePlus
S672 Phosphorylation PhosphoSitePlus
S678 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S685 Phosphorylation PhosphoSitePlus
T686 Phosphorylation PhosphoSitePlus
T697 O-Glycosylation GlyGen 30379171, 32574038, 31492838, ...29351928, 35132862, 35254053, 28657654, 29237092, 30059200
T699 O-Glycosylation GlyGen 30379171, 32574038, 31492838, ...29351928, 35132862, 35254053, 28657654, 29237092, 30059200
K710 Ubiquitination PhosphoSitePlus
T727 Phosphorylation PhosphoSitePlus
S735 O-Glycosylation GlyGen 31373491
T775 O-Glycosylation GlyGen 30379171, 32574038, 31492838, ...29351928, 35132862, 35254053, 28657654, 29237092, 30059200
T778 O-Glycosylation GlyGen 30379171, 32574038, 31492838, ...29351928, 35132862, 35254053, 28657654, 29237092, 30059200
S782 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S784 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243
K789 Acetylation PhosphoSitePlus
T793 O-Glycosylation GlyGen 30379171, 32574038, 31492838, ...29351928, 35132862, 35254053, 28657654, 29237092, 30059200
S794 O-Glycosylation GlyGen 30379171, 32574038, 31492838, ...29351928, 35132862, 35254053, 28657654, 29237092, 30059200
S794 Phosphorylation PhosphoSitePlus
T795 Phosphorylation PhosphoSitePlus
Y796 Phosphorylation PhosphoSitePlus
T799 O-Glycosylation GlyGen 30379171, 32574038, 31492838, ...29351928, 35132862, 35254053, 28657654, 29237092, 30059200
T799 Phosphorylation PhosphoSitePlus
T802 O-Glycosylation GlyGen 32574038
S804 O-Glycosylation GlyGen 32574038
S804 Phosphorylation PhosphoSitePlus
T809 O-Glycosylation GlyGen 34846842
S820 Phosphorylation PhosphoSitePlus
K847 Ubiquitination PhosphoSitePlus
Y864 Phosphorylation PhosphoSitePlus
T867 Phosphorylation PhosphoSitePlus
S870 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T33 Phosphorylation HPRD 20068231
S75 Phosphorylation HPRD 19651622, 18669648, 20068231
T78 Phosphorylation HPRD 19651622, 20068231
T79 Phosphorylation HPRD 19651622, 18669648, 20068231
S86 Phosphorylation HPRD 20068231
T202 Phosphorylation HPRD 20068231
S378 Phosphorylation HPRD 20068231
S430 Phosphorylation HPRD 18510355, 19651622, 19664994, ...20068231
T475 Phosphorylation HPRD 18669648
S510 Phosphorylation HPRD 20068231
S540 Phosphorylation HPRD 18669648, 18212344, 20068231
S541 Phosphorylation HPRD 18669648
S544 Phosphorylation HPRD 18510355, 18669648, 20068231
S546 Phosphorylation HPRD 18510355, 18669648, 18212344, ...20068231
T550 Phosphorylation HPRD 20068231
S564 Phosphorylation HPRD 20068231
S578 Phosphorylation HPRD 18669648, 20068231
S639 Phosphorylation HPRD 19651622
S648 Phosphorylation HPRD 17322306, 18510355, 18669648, ...19651622, 20068231
S650 Phosphorylation HPRD 17322306, 19651622, 18669648, ...20068231
S678 Phosphorylation HPRD 18510355, 18669648, 19664994, ...20068231
T686 Phosphorylation HPRD 17322306, 20068231
S782 Phosphorylation HPRD 18669648, 20068231
S784 Phosphorylation HPRD 16964243, 18767875, 19664994, ...17322306, 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation HPRD 19651622, 18669648, 20068231
T16 Phosphorylation HPRD 19651622, 20068231
T17 Phosphorylation HPRD 19651622, 18669648, 20068231
S24 Phosphorylation HPRD 20068231
T140 Phosphorylation HPRD 20068231
Y281 Phosphorylation PhosphoSitePlus
S316 Phosphorylation HPRD 20068231
S368 Phosphorylation HPRD 18510355, 19651622, 19664994, ...20068231
T413 Phosphorylation HPRD   PhosphoSitePlus 18669648
K421 Ubiquitination PhosphoSitePlus
K432 Methylation PhosphoSitePlus
S436 Phosphorylation HPRD   PhosphoSitePlus 20068231
S466 Phosphorylation HPRD   PhosphoSitePlus 18669648, 18212344, 20068231
S467 Phosphorylation HPRD 18669648
S470 Phosphorylation HPRD   PhosphoSitePlus 18510355, 18669648, 20068231
S472 Phosphorylation HPRD   PhosphoSitePlus 18510355, 18669648, 18212344, ...20068231
T476 Phosphorylation HPRD 20068231
S490 Phosphorylation HPRD 20068231
S504 Phosphorylation HPRD 18669648, 20068231
Y554 Phosphorylation PhosphoSitePlus
S565 Phosphorylation HPRD 19651622
S574 Phosphorylation HPRD 17322306, 18510355, 18669648, ...19651622, 20068231
S576 Phosphorylation HPRD 17322306, 19651622, 18669648, ...20068231
S604 Phosphorylation HPRD 18510355, 18669648, 19664994, ...20068231
T612 Phosphorylation HPRD 17322306, 20068231
S657 Phosphorylation PhosphoSitePlus
S680 Phosphorylation HPRD 18669648, 20068231
S682 Phosphorylation HPRD 16964243, 18767875, 19664994, ...17322306, 18669648, 20068231
Y694 Phosphorylation PhosphoSitePlus
Y762 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K14 Ubiquitination PhosphoSitePlus
Y37 Phosphorylation PhosphoSitePlus
T444 Phosphorylation PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus
K463 Methylation PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
T507 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S13 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S13 L13 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S24 L24 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ]
S50 F50 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S69 N69 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S75 L75 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S75 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S86 L86 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ]
K92 N92 Biomuta DOID:363 / uterine cancer [ icgc ]
S107 L107 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S316 C316 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S378 C378 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S391 F391 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S396 G396 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
K421 N421 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S441 L441 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
K452 N452 Biomuta DOID:363 / uterine cancer [ cosmic ]
S466 T466 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S466 C466 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S467 F467 Biomuta DOID:4159 / skin cancer [ cosmic ]
S472 F472 Biomuta DOID:4159 / skin cancer [ cosmic ]
T489 R489 Biomuta DOID:3571 / liver cancer [ cosmic ]
T489 M489 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S490 F490 Biomuta DOID:4159 / skin cancer [ cosmic ]
S503 F503 Biomuta DOID:4159 / skin cancer [ cosmic ]
S504 R504 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S523 N523 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S540 T540 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S540 C540 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S541 F541 Biomuta DOID:4159 / skin cancer [ cosmic ]
S546 F546 Biomuta DOID:4159 / skin cancer [ cosmic ]
S564 F564 Biomuta DOID:4159 / skin cancer [ cosmic ]
S574 R574 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S574 I574 Biomuta DOID:363 / uterine cancer [ cosmic ]
S576 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S576 L576 Biomuta DOID:1324 / lung cancer [ icgc ]
S578 R578 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S604 N604 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S648 I648 Biomuta DOID:363 / uterine cancer [ cosmic ]
S648 R648 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S650 L650 Biomuta DOID:1324 / lung cancer [ icgc ]
S650 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K663 M663 Biomuta DOID:1324 / lung cancer [ cosmic ]
S678 N678 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S680 F680 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S685 F685 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S782 F782 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T799 N799 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
T799 S799 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S804 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S820 C820 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]