iPTMnet Report Q9H4A3 WNK1

Q9H4A3 (WNK1) as Substrate

Expanded View

Site	PTM Type	PTM Enzyme	Score	Source	PMID
S2	Phosphorylation		score1	PhosphoSitePlus
S10	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S11	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S11	Phosphorylation		score1	PhosphoSitePlus
T12	Phosphorylation		score1	PhosphoSitePlus
S15	Phosphorylation		score3	PhosphoSitePlus UniProt	17190791
S19	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 23186163, 20068231
S33	Phosphorylation		score1	PhosphoSitePlus
T60	Phosphorylation	O00141 (SGK1) , P31749 (AKT1) , O75582 (RPS6KA5)	score4	neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor	14611643, 16081417, 29930759, ...21355052
R66	Methylation		score1	PhosphoSitePlus
T71	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
T73	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
T74	Phosphorylation		score1	PhosphoSitePlus
S167	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S167	Phosphorylation		score4	phospho.ELM PhosphoSitePlus UniProt	17525332, 23186163, 24275569, ...17190791
S170	Phosphorylation		score1	PhosphoSitePlus
S174	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	17525332, 23186163, 24275569
S183	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S183	Phosphorylation		score1	PhosphoSitePlus
S185	Phosphorylation		score1	PhosphoSitePlus
S189	Phosphorylation		score1	PhosphoSitePlus
S198	Phosphorylation		score1	PhosphoSitePlus
S231	Phosphorylation		score1	PhosphoSitePlus
S306	Phosphorylation		score1	PhosphoSitePlus
T308	Phosphorylation		score1	PhosphoSitePlus
T373	Phosphorylation		score1	PhosphoSitePlus
K375	Ubiquitination		score1	PhosphoSitePlus
S378	Phosphorylation	Q9H4A3 (WNK1)	score4	IEDB neXtProt phospho.ELM PhosphoSitePlus UniProt	17081983, 33936100, 31656913, ...12374799, 32387766, 29493099, 27869121
S382	Phosphorylation	Q9BYP7 (WNK3) , Q9Y3S1 (WNK2) , Q9H4A3 (WNK1)	score4	neXtProt PhosphoSitePlus RLIMS-P Signor UniProt	16832045, 34289367, 17190791, ...31656913, 15883153, 22032326, 29176664, 16263722, 18270262, 12374799
T436	O-Glycosylation		score1	GlyGen	30379171
S437	O-Glycosylation		score1	GlyGen	30379171
S599	Phosphorylation		score1	PhosphoSitePlus
S679	Phosphorylation		score1	PhosphoSitePlus
T1098	Phosphorylation		score1	PhosphoSitePlus
Y1102	Phosphorylation		score1	PhosphoSitePlus
K1104	Acetylation		score1	PhosphoSitePlus
S1105	Phosphorylation		score1	PhosphoSitePlus
S1108	Phosphorylation		score1	PhosphoSitePlus
S1110	Phosphorylation		score1	PhosphoSitePlus
T1115	Phosphorylation		score1	PhosphoSitePlus
S1116	Phosphorylation		score1	PhosphoSitePlus
K1119	Acetylation		score1	PhosphoSitePlus
K1128	Acetylation		score1	PhosphoSitePlus
Y1215	Phosphorylation		score1	PhosphoSitePlus
S1220	Phosphorylation		score1	PhosphoSitePlus
S1234	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1235	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 32938750, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
T1244	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1245	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 32938750, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1246	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
T1248	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1253	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1253	Phosphorylation		score1	PhosphoSitePlus
S1261	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1261	Phosphorylation		score4	phospho.ELM PhosphoSitePlus RLIMS-P UniProt	23186163, 16964243, 17190791, ...18669648, 20068231, 22032326
S1276	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
T1279	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
T1281	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1285	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1285	Phosphorylation		score1	PhosphoSitePlus
S1289	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1295	Phosphorylation		score1	PhosphoSitePlus
S1297	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	18220336
S1299	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1300	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	18220336
T1521	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1543	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1558	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1559	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1562	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
K1653	Ubiquitination		score1	PhosphoSitePlus
K1658	Ubiquitination		score1	PhosphoSitePlus
S1681	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
T1687	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
T1695	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
T1757	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
T1810	Phosphorylation		score1	PhosphoSitePlus
T1812	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1813	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
T1827	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1838	Phosphorylation		score1	PhosphoSitePlus
T1848	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 32938750, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
T1848	Phosphorylation		score3	PhosphoSitePlus UniProt	17190791
S1849	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 32938750, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1849	Phosphorylation		score1	PhosphoSitePlus
S1850	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1863	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 32938750, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1887	Phosphorylation		score1	PhosphoSitePlus
T1929	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1931	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1935	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1935	Phosphorylation		score1	PhosphoSitePlus
T1937	Phosphorylation		score1	PhosphoSitePlus
T1941	Phosphorylation		score1	PhosphoSitePlus
T1949	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
T1950	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
T1951	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S1959	Phosphorylation		score1	PhosphoSitePlus
S1961	Phosphorylation		score1	PhosphoSitePlus
T1963	Phosphorylation		score1	PhosphoSitePlus
T1968	Phosphorylation		score1	PhosphoSitePlus
T1970	Phosphorylation		score1	PhosphoSitePlus
S1978	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	20068231, 18669648, 19690332, ...24275569
S2002	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 17081983
S2005	Phosphorylation		score1	PhosphoSitePlus
S2011	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 17081983
S2012	Phosphorylation		score4	phospho.ELM PhosphoSitePlus RLIMS-P UniProt	18669648, 17081983, 17190791
S2027	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 21406692, 24275569
S2029	Phosphorylation		score4	phospho.ELM PhosphoSitePlus RLIMS-P UniProt	18669648, 23186163, 21406692, ...17190791
S2032	Phosphorylation	P42345 (MTOR)	score4	phospho.ELM PhosphoSitePlus RLIMS-P UniProt	21406692, 23186163, 17081983, ...17190791, 18669648, 21659604, 20068231
S2037	Phosphorylation		score1	PhosphoSitePlus
S2038	Phosphorylation		score1	PhosphoSitePlus
S2065	Phosphorylation		score1	PhosphoSitePlus
Y2102	Phosphorylation		score1	PhosphoSitePlus
S2121	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 20068231
T2128	Phosphorylation		score1	PhosphoSitePlus
S2145	Phosphorylation		score1	PhosphoSitePlus
K2243	Ubiquitination		score1	PhosphoSitePlus
T2245	Phosphorylation		score1	PhosphoSitePlus
T2247	Phosphorylation		score1	PhosphoSitePlus
S2265	Phosphorylation		score1	PhosphoSitePlus
S2270	Phosphorylation		score1	PhosphoSitePlus
Y2276	Phosphorylation		score1	PhosphoSitePlus
S2286	Phosphorylation		score1	PhosphoSitePlus
S2294	Phosphorylation		score1	PhosphoSitePlus
S2302	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S2306	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S2358	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S2370	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S2370	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
S2372	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
S2372	Phosphorylation		score4	PhosphoSitePlus RLIMS-P UniProt	23186163, 17190791
S2377	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
R2380	Methylation		score1	PhosphoSitePlus
T2381	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223
T2382	O-Glycosylation		score1	GlyGen	23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 34725712, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 36240223

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K25	Sumoylation		score1	PhosphoSitePlus

Site	PTM Type	Score	Source
S780	Phosphorylation	score1	PhosphoSitePlus
S847	Phosphorylation	score1	PhosphoSitePlus
S1009	Phosphorylation	score1	PhosphoSitePlus
S1015	Phosphorylation	score1	PhosphoSitePlus
S1035	Phosphorylation	score1	PhosphoSitePlus
S2071	Phosphorylation	score1	PhosphoSitePlus

UniProt AC / UniProt ID	Q9H4A3 / WNK1_HUMAN
Protein Name	Serine/threonine-protein kinase WNK1
Gene Name	Name: WNK1 Synonyms:HSN2;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9H4A3 DAG View
PRO Name	serine/threonine-protein kinase WNK1 (human)
Definition	A serine/threonine-protein kinase WNK1 that is encoded in the genome of human.
Short Label	hWNK1
Category	organism-gene

Substrate	Site	Score	Source	PMID
O95747 (OXSR1)	T185	score4	neXtProt phospho.ELM PhosphoSitePlus Signor	24191005, 16083423, 17190791
O95747 (OXSR1)	S325	score4	phospho.ELM PhosphoSitePlus Signor	24191005, 16083423, 17190791
Q15796 (SMAD2)	S110	score2	neXtProt	17392271
Q15796 (SMAD2)	S260	score2	neXtProt	17392271
Q15796 (SMAD2)	S465	score2	neXtProt	17392271
Q8N9I0 (SYT2)	T199	score3	neXtProt Signor	15350218
Q8N9I0 (SYT2)	T383	score2	neXtProt	15350218
Q9H4A3 (WNK1)	S378	score4	neXtProt UniProt	31656913, 12374799
Q9H4A3 (WNK1)	S382	score4	neXtProt PhosphoSitePlus Signor UniProt	15883153, 18270262, 22032326, ...12374799, 17190791
Q9UEW8 (STK39)	T231	score4	neXtProt PhosphoSitePlus Signor	17190791, 16083423, 16263722
Q9UEW8 (STK39)	S371	score4	neXtProt PhosphoSitePlus Signor	17190791, 18270262, 16083423, ...16263722
Q9UHW9 (SLC12A6)	T991	score3	neXtProt PhosphoSitePlus Signor	19665974
Q9UHW9 (SLC12A6)	T1048	score3	neXtProt PhosphoSitePlus Signor	19665974

Site	Variant	Source	Disease [Sample source]
T12	A12	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
T60	I60	Biomuta	DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R66	L66	Biomuta	DOID:8618 / oral cavity cancer [ cosmic ]
T74	A74	Biomuta	DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S167	F167	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S437	R437	Biomuta	DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S780	C780	Biomuta	DOID:1612 / breast cancer [ cosmic ]
S847	N847	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S1035	Y1035	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
T1098	I1098	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
S1110	C1110	Biomuta	DOID:5041 / esophageal cancer [ cosmic ]
S1235	F1235	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S1246	Y1246	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
S1253	F1253	Biomuta	DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S1289	N1289	Biomuta	DOID:4362 / cervical cancer [ icgc ]
S1297	C1297	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
S1299	L1299	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S1300	C1300	Biomuta	DOID:263 / kidney cancer [ cosmic, icgc ]
S1300	P1300	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
S1558	C1558	Biomuta	DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S1562	F1562	Biomuta	DOID:363 / uterine cancer [ icgc ]
S1562	Y1562	Biomuta	DOID:9256 / colorectal cancer [ cosmic, icgc ]
K1653	M1653	Biomuta	DOID:3571 / liver cancer [ cosmic ]
S1849	N1849	Biomuta	[ cosmic ]
T1970	P1970	Biomuta	DOID:9256 / colorectal cancer [ cosmic, icgc ]
S2002	A2002	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
S2005	L2005	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
S2145	N2145	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
S2265	L2265	Biomuta	DOID:4362 / cervical cancer [ cosmic, icgc ]
S2306	F2306	Biomuta	DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S2370	F2370	Biomuta	DOID:4159 / skin cancer [ cosmic, icgc ]
S2377	T2377	Biomuta	DOID:2531 / hematologic cancer [ cosmic ]
R2380	Q2380	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
T2382	P2382	Biomuta	DOID:263 / kidney cancer [ cosmic ]

iPTMnet Report for Q9H4A3 (WNK1)

Protein Information

Interactive Sequence View

Q9H4A3 (WNK1) as Substrate

Q9H4A3 (WNK1) as PTM Enzyme

PTM sites affected in variants

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms