iPTMnet Report for Q9H467 (CUEDC2)
Protein Information
| UniProt AC / UniProt ID | Q9H467 / CUED2_HUMAN |
| Protein Name | CUE domain-containing protein 2 |
| Gene Name | Name: CUEDC2 Synonyms:C10orf66;ORFNames:HOYS6; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H467 |
| PRO Name | CUE domain-containing protein 2 (human) |
| Definition | A CUE domain-containing protein 2 that is encoded in the genome of human. |
| Short Label | hCUEDC2 |
| Category | organism-gene |
Q9H467 (CUEDC2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K82 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K93 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S110 | Phosphorylation | P06493 (CDK1) | score4 | HPRD neXtProt PhosphoSitePlus UniProt | 21743465, 20068231 | |
| K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K186 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K209 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K213 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K219 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K230 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K238 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S254 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T255 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| K256 | Sumoylation | score1 | PhosphoSitePlus | |||
| K256 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K261 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K272 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T274 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y275 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K279 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K82 | R82 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K238 | N238 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T255 | I255 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K256 | T256 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K272 | N272 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |
DAG View