iPTMnet Report Q9H461 FZD8

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q9H461 / FZD8_HUMAN
Protein Name	Frizzled-8 precursor
Gene Name	Name: FZD8
Organism	Homo sapiens (Human)

PRO ID	PR:Q9H461 DAG View
PRO Name	frizzled-8 (human)
Definition	A frizzled-8 that is encoded in the genome of human.
Short Label	hFZD8
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9H461 (FZD8) as Substrate

Q9H461

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
		Ubiquitination		score1	PRO
	Y376	Phosphorylation		score1	PhosphoSitePlus
	K515	Ubiquitination		score1	PhosphoSitePlus
	Y540	Phosphorylation		score1	PhosphoSitePlus
	T541	Phosphorylation		score1	PhosphoSitePlus

Proteoforms

	PRO ID (Short Label)	Sites	PTM Enzyme	Source	PMID
	PR:000047480 (hFZD8/SigPep-/UbiqLys+)	ub		PRO

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
Y376	C376	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
T541	I541	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]