iPTMnet Report for Q9H444 (CHMP4B)
Protein Information
| UniProt AC / UniProt ID | Q9H444 / CHM4B_HUMAN |
| Protein Name | Charged multivesicular body protein 4b |
| Gene Name | Name: CHMP4B Synonyms:C20orf178,SHAX1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H444 |
| PRO Name | charged multivesicular body protein 4b (human) |
| Definition | A charged multivesicular body protein 4b that is encoded in the genome of human. |
| Short Label | hCHMP4B |
| Category | organism-gene |
Q9H444 (CHMP4B) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S2 | Acetylation | score1 | UniProt | 22814378 | ||
| S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K6 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K6 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K14 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K17 | Acetylation | score1 | PhosphoSitePlus | |||
| K17 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K38 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K70 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S87 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T103 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y111 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K114 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K114 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K117 | Methylation | score1 | PhosphoSitePlus | |||
| S184 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 20068231 | ||
| T188 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| S196 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S201 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K202 | Acetylation | score1 | PhosphoSitePlus | |||
| K202 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S223 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 21406692, 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S2 | L2 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
| K55 | N55 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S87 | L87 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S87 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| Y111 | C111 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S201 | * | Biomuta | DOID:1319 / brain cancer [ cosmic ] |
DAG View