Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H400 / LIME1_HUMAN
Protein Name Lck-interacting transmembrane adapter 1
Gene Name Name: LIME1
Synonyms:LIME;ORFNames:LP8067;
Organism Homo sapiens (Human)

PRO ID PR:Q9H400
DAG View
PRO Name lck-interacting transmembrane adapter 1 (human)
Definition An lck-interacting transmembrane adapter 1 that is encoded in the genome of human.
Short Label hLIME1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H400 (LIME1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S54 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
T66 Phosphorylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
S95 Phosphorylation PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus
Y167 Phosphorylation PhosphoSitePlus   UniProt 14610046
Y200 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18083107, 14610046
S201 Phosphorylation PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
Y235 Phosphorylation PhosphoSitePlus
T237 Phosphorylation PhosphoSitePlus
Y254 Phosphorylation PhosphoSitePlus   UniProt 14610046
S256 Phosphorylation PhosphoSitePlus   UniProt 24275569
T274 Phosphorylation PhosphoSitePlus
R288 Methylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y167 Phosphorylation HPRD 19901323
Y200 Phosphorylation HPRD 19901323
S201 Phosphorylation HPRD 19901323


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T66 I66 Biomuta DOID:4362 / cervical cancer [ cosmic ]
K205 E205 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T237 I237 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
Y254 D254 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T274 A274 Biomuta DOID:263 / kidney cancer [ icgc, tcga ]
S293 Y293 Biomuta DOID:1909 / melanoma [ tcga ] DOID:11054 / urinary bladder cancer [ tcga ]